Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17348 Fostamatinib GSE70138 MCF10A Human 24h 0.12uM EID0020
Types Number Response transcription factors
Up-regulation 61 HDAC6; NFIL3; INSM1; ST18; ZFPM2; NHLH2; CEBPD; ESRRG; EGR1; GLI2; MZF1; SMARCB1; BNC2; SALL1; NEUROD1; SHOX2; FOXA2; HAND1; TOX; IRF8; ACTL6B; MYCN; MEIS2; LEF1; MYRF; BACH2; CREB3L1; HOXB5; ZBTB20; LOXL2; SSBP3; WT1; NPAS2; NR4A1; HOXB6; ZNF264; PBX1; TCF21; CRYM; ZBTB38; TOX3; SNAI2; MYT1L; ZSCAN18; NR4A2; ZBTB16; KLF5; ARNT2; MEIS1; BCL11A; ZEB1; PBX3; GATA6; TRIB3; DACH1; SATB1; FOS; SOX2; HEY1; POU2AF1; DMTF1
Down-regulation 21 ADRB2; REST; RBPMS; HDAC1; STAT3; YBX3; URI1; TRPS1; DNMT3B; HOXC6; HOXC10; HIPK3; AFF1; TRIP6; KLF10; AEBP1; TOB1; NRBF2; MYB; TWIST1; CREB1