Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17341 Gsk-1059615 GSE70138 MCF10A Human 24h 1.11uM EID0020
Types Number Response transcription factors
Up-regulation 88 TSC22D3; HDAC6; SOX4; MZF1; HDAC7; ZMYM2; SMAD6; ZNF768; JUP; YEATS2; TP63; ING4; CALCOCO1; ZNF544; FOXO4; BPTF; STAT2; ELF3; MED15; PBXIP1; ZNF133; TGFB1I1; TCEA2; SETDB1; ZNF226; MED12; TGIF1; ZNF688; TAL1; TRIM29; ZNF467; HBP1; PNRC1; ZNF580; ZNF611; RBFOX2; NR1H4; TLE4; SREBF1; MED14; SMAD3; POU2AF1; ARID1A; FOXO3; MYRF; HSF1; SSBP3; FOXO1; AES; TRIM22; CEBPD; ZNF83; TSC22D1; HOXD1; TFEC; SMARCC2; ZNF264; KLF5; SAP18; DLX5; ID2; ARNT2; PAX5; ATN1; BTG1; FOXN3; NR1H3; POU4F1; ST18; FLNA; NCOA3; ZBTB16; IRF9; IFI16; KLF11; ZNF423; TFAP2C; ZBTB20; MECOM; TBX3; TGFB1; TRIB3; SMAD1; TXNIP; MEIS2; HMG20B; ID1; FOS
Down-regulation 43 FOSL1; CCNA2; NRIP1; CHD7; CRY1; HNRNPD; GATAD2A; LEF1; EDF1; PSMC3IP; DNAJC2; SUB1; RBM14; PTTG1; ING3; TBPL1; ING2; SFPQ; CCDC59; TFAM; STAT3; EED; BCLAF1; HMGB2; ASCL1; PITX1; AFF1; XBP1; ZBTB18; CREM; MYBL2; CITED1; ZIC1; SATB2; RBBP8; EGR3; PBX3; SERTAD2; TOX3; IRX5; SOX9; CREB1; KDM5D