Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17321 Alvocidib GSE70138 MCF10A Human 24h 0.04uM EID0020
Types Number Response transcription factors
Up-regulation 122 TSC22D3; VGLL4; TP63; PHF20; ING4; PNRC1; ZNF345; ZKSCAN4; ZNF444; ZNF141; MYCL; ZNF665; ZFP36L2; TCEA2; PRDM2; ZNF33B; ZNF529; CBX7; OSR2; CBFA2T3; PAWR; YEATS2; ZNF580; TCF7L1; NFATC4; CEBPD; GATA2; DLX5; ZNF34; TRPS1; TRIM16; CREBL2; PEX14; HBP1; REPIN1; ZNF423; KLF13; CALCOCO1; NFKB2; SOX3; ZNF623; HIRA; EHF; PPP1R13L; CDIP1; ZNF117; TRIM29; THRA; ZNF239; IRF6; HDAC5; RBFOX2; SETDB1; BCL6; SALL2; HOXD1; MXI1; FOXO3; HAND1; JUP; ZNF573; PFDN5; KLF11; TCF25; BCL11A; SOX17; MNDA; HDAC9; ERBB4; PHF1; TDP2; ZNF83; JUN; ZNF415; ZSCAN18; BTG1; GATA6; CDYL; RXRA; KLF4; ESR1; ELF4; SSX1; HIC2; EYA1; ZSCAN31; BRD4; VPS72; TLE1; MYRF; CUX2; ARNT2; TCF7L2; ZNF43; CRYM; ATF3; LIN28A; DACH1; ZHX2; BACH2; TFEC; SP110; TFAP2C; ZBTB16; TGFB1I1; MECOM; IRF9; MAFB; ELF3; PBX1; ZNF512B; SNAI2; ZNF91; FOXG1; MEIS1; WT1; SSBP2; TRIB3; FOS; BASP1; HEY1; TXNIP
Down-regulation 72 FOSL1; CCNA2; EZH2; TFDP1; TCERG1; RBM14; BCLAF1; ATF5; BRCA1; ARID4B; CENPF; HNRNPD; IKBKAP; SUB1; SMARCC1; PMF1; ATF1; BMI1; BLM; MYBL2; CHAF1B; RBBP4; SFPQ; HOXB7; CBFB; PITX1; RBL1; C1QBP; RBPMS; PURA; ING3; PSMC3IP; EED; PA2G4; NPM1; YWHAB; PRKDC; BAZ1A; HOXA5; ASH2L; NFKB1; CLOCK; CBX3; SMARCA2; TFAM; CCDC59; HMGB1; YEATS4; NFIB; HOXC6; HMGB2; WWTR1; HOXC4; DNMT3B; HLTF; NR2F1; PTTG1; SIX1; CITED1; FOXM1; CTR9; TEAD1; TSC22D2; ELK3; ZBTB38; NR2F2; FOXD1; HOXC10; EGR3; HOXB6; KDM5D; CREB1