Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17314 Geldanamycin GSE70138 MCF10A Human 24h 1.11uM EID0019
Types Number Response transcription factors
Up-regulation 360 MNAT1; CALCOCO1; HBP1; ZMIZ1; ZFHX3; PNRC1; BPTF; PBXIP1; PBX1; JUP; AES; IRF9; HDAC5; SALL2; TSC22D3; HEY1; ZKSCAN4; ZNF345; ZNF117; ING4; RSF1; HOXB3; SOX13; ZNF467; BAZ2B; EZH1; NCOA2; IRF6; TAF1C; HOXA3; TCF25; TRIM22; LDB1; CREBL2; TCEA2; MZF1; ZNF76; RXRB; SMARCC2; KAT2B; RING1; GRHL2; ZBTB44; ARHGAP35; AR; SETDB1; ZNF768; EP300; LZTR1; CHD9; NAB2; SIX3; STAT2; HMBOX1; ERBB4; CBX7; ZNF223; HOXA4; ZSCAN9; TFAP2A; TRIP11; CEBPA; ZNF358; MED25; BARX1; NFATC4; DBP; CBFA2T2; MEIS2; TBX6; HOXB2; ZNF500; CIR1; MYCL; RARB; ELF4; BAZ2A; ZNF175; EHMT2; EPAS1; MED12; HOXD1; ZNF446; NFE2L1; NR1H2; ZNF155; SRCAP; HMGN3; ZFHX2; ZNF606; RORC; ZNF580; NFATC3; SUPT6H; HINFP; RAX; TP63; CIC; TBX19; ZNF362; PFDN5; TBX5; SIRT2; HIF3A; NR4A1; EYA1; CNOT3; RARG; PRDM2; ZNF225; TCF7L1; TRAK1; ZNF512B; TFAP2C; SPI1; TSHZ2; ZNF91; LHX3; TP73; ZNF444; ASCL3; ZNF384; OVOL2; PHF1; HSF4; ZNF112; MED23; POU2F1; NR5A1; SREBF2; HOXB1; TLX1; TP53; ZNF12; MAZ; SP2; TBX10; ARID3A; CRX; TEAD3; ARID1A; ZNF219; ZNF33B; ZNF611; ZNF224; HOXB5; HESX1; PPARA; ZNF629; NFAT5; ZNF75D; ARNT2; PRDM14; ZNF34; ID4; KLF13; SOX18; FLI1; CDIP1; ERBB2; SOX3; ESR2; APBB1; SUPT5H; ZKSCAN8; ZNF85; CRTC1; ZSCAN31; PHIP; THRB; HOXA5; SUPT7L; MLXIPL; TULP1; ZBTB7A; CSDC2; CERS4; PRDM12; MEOX1; CARF; ZNF337; ZNF268; DYRK1B; SIM1; TLE2; TRIM29; SOX17; ATN1; PAX8; ZNF688; ZNF331; TULP3; FOXN3; LITAF; CREB3L2; ZBTB7B; MED15; SIN3B; REPIN1; ZNF133; GBX1; HMG20B; ZNF205; BRD4; MEF2D; ARID5A; ZHX2; TFEC; CBX4; SIX1; ZBTB17; TRIB3; KDM5C; ELF3; CBFA2T3; HR; NR1I3; ZNF74; ZNF536; KDM4C; DLX5; TCF4; MED14; ZNF667; SUPT4H1; TFCP2; HMX1; MKL1; SLC2A4RG; KLF3; VPS72; CUX2; DLX4; ST18; PIAS4; TGFB1; CIITA; CITED2; ZNF350; SMARCD1; ZMYND8; MYOG; DDX17; ZNF665; HEY2; PLAGL1; ZNF135; SHOX2; ATOH1; RFX2; ZNF304; MDM2; ZNF141; MED16; ZSCAN18; JUND; STAT6; ZNF324; ZNF544; SSBP3; L3MBTL1; PDLIM1; MAF; ZNF254; TCF15; ZNF160; ZNF44; TCF12; KDM5B; ZNF248; TCF7L2; SP140L; MECP2; RBFOX2; BTG1; RXRA; TBX21; BCL11A; TAL1; MECOM; ZMIZ2; DDIT3; NFKB2; CHD8; SALL1; SPEN; THRA; IRF7; TERF1; NR1H4; BCL6; TXNIP; ZNF93; CDYL; TRPS1; OSR2; OLIG2; TOB1; INSR; NAB1; KLF1; HOXD3; NR0B1; BNC2; ZNF711; KLF11; TLE4; ZNF83; STAT1; MYRF; SOX10; SMAD6; FOXO4; ZBTB20; PKNOX2; EHF; MXI1; PAX6; TSG101; RERE; RBL2; ZKSCAN1; MITF; GLI2; ARID4B; SIX2; INSM1; ZNF165; MED13; POU2AF1; NR4A2; ASCL1; CUX1; MKL2; NR3C1; ZNF652; FOXA1; REL; ZNF43; TOX3; IRF8; TGIF1; ZNF264; ARID5B; TBX3; ELF5; FOXF1; ESR1; MYCN; RYBP; SSBP2; HDAC9; CRYM; EMX2; SMARCA1; KAT6B; MSX1; KLF5; MEF2C; GATA3
Down-regulation 126 FOSL1; CCNA2; HMGA2; RUVBL1; ADRB2; MYBL2; MYCBP; NUP62; MYC; TCERG1; EGR1; FHL2; SUV39H1; CHAF1B; RBL1; TBP; PSMC3IP; NFIL3; EZH2; PARP1; RBM14; MED7; PPRC1; TFAM; TAF9; RNF14; SSRP1; CBFB; RNF138; HOXA10; KLF10; ZBTB18; CRY1; CEBPG; YWHAB; WDHD1; BCLAF1; TAF1A; BAZ1A; EGR3; LEF1; EDF1; ELK3; HSF2; FOXM1; YEATS4; WHSC1; MED27; WDR77; SFPQ; BRCA1; TFDP1; NPM1; BIRC2; HNRNPD; PREB; CHD1; DR1; TEAD4; HMGB1; PTTG1; RAN; NRBF2; PMS1; DRAP1; C1QBP; KLF6; BLM; TSC22D2; PA2G4; TRIM32; ZNF200; TERF2; KMT5A; ETS1; ITGB3BP; UBP1; NKX3-1; CEBPZ; DNAJC2; NFKB1; TBPL1; HLTF; BMI1; PURA; ZNF593; ZFP36L2; ARNTL2; JUNB; ID2; PRKDC; SMARCA4; PQBP1; XBP1; E2F3; BATF3; RUNX1; ING2; NFIB; SAP30; RUVBL2; RNF4; TCFL5; SF1; SUB1; SMAD1; FOXD1; KLF2; EGR2; JUN; WWTR1; BCL11B; CHD7; ETV1; HMGB3; MYBL1; DMTF1; SNAI2; PPARG; HOXC6; DLX2; NR2F1; ZBTB38; HMGA1; MAFB; SATB1