Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17312 Geldanamycin GSE70138 MCF10A Human 24h 10uM EID0019
Types Number Response transcription factors
Up-regulation 293 PBXIP1; CALCOCO1; BPTF; PNRC1; CREG1; NCOA2; RSF1; TSC22D3; HOXB2; AR; ING4; HBP1; ZNF345; NFAT5; MED25; RING1; KAT2B; NFE2L1; ZNF384; ZNF117; EZH1; PRDM2; SIRT2; CBX7; NFATC3; FOXN3; CHD9; TRIM22; RAX; ZNF12; TCEA2; IRF9; HMG20B; WNT4; HMBOX1; ZKSCAN4; CASZ1; RARB; ZNF223; LHX3; DBP; CRTC1; TBX10; ZNF768; SRCAP; MLXIPL; BAZ2B; CBFA2T2; HOXB3; ZNF358; EYA1; FOXJ2; MYOG; HOXB5; AFF2; PBX1; RARG; HDAC5; MEIS2; TFE3; TLE4; MYF5; RXRB; HOXA4; HEY1; HOXA3; PHF1; ZMIZ1; HINFP; PAX8; ZNF154; TSHZ2; TBX19; SP4; ZNF34; LZTR1; ZNF444; RORC; IKZF4; MZF1; ELF3; ZKSCAN8; TRIP11; SREBF2; ZNF175; BTG1; KLF13; JUP; ZBTB44; IRF6; PLAGL1; YBX2; RFX7; ZNF446; TBX4; PPARD; BAZ2A; RFX2; FOXI1; HIF3A; SIM1; HOXB1; SIX3; HMX1; RXRA; ZNF155; EBF2; CDIP1; ZSCAN31; ZNF8; POU2F1; CREBL2; ZNF219; MYOD1; MED23; CERS4; PEX14; BRWD1; MDM2; HSF4; ZNF688; APBB1; POU2AF1; RXRG; TULP1; SUPT4H1; ZFHX2; MEN1; STAT2; PKNOX2; MED14; PRDM1; ATOH1; PRDM14; ARNT; DLX4; ERBB2; NR0B2; CBFA2T3; TEAD3; ZBTB7B; TLX1; CIITA; TXNIP; ZNF606; ZNF500; MAF; ZNF112; LITAF; NAB2; ZNF536; ZNF33B; ID4; TADA3; SALL2; ELF2; ZNF292; HOXA5; CSDC2; EHMT2; RNF10; CEBPA; KAT8; ZNF184; OSR2; NR1H2; PDLIM1; CDX2; GRHL2; MEIS1; CIR1; SOX21; TCF25; ZNF133; MBD4; THRB; NR5A2; ZNF177; E2F2; THRA; ZFX; ZNF83; RLF; TBX21; ZNF337; CBX4; SIAH2; SP2; CREB3L2; BARX1; ZNF512B; ZFP64; ZNF189; ZNF91; BACH1; OVOL2; HEY2; TCF7; DDIT3; MITF; ZNF85; TRPS1; ZNF211; CUX1; FOXO4; ZNF329; TFEB; SATB1; ZNF467; FOXA2; SSBP3; GFI1B; ZSCAN18; TFDP2; ZHX2; KLF1; ZNF611; ALX1; HIPK1; ZNF580; TCF7L1; NCOA1; TCF15; TRIM29; ZNF529; TGFB1I1; MXD4; ARID4B; BRD2; ZKSCAN1; ZNF667; RBPJ; TP63; IRF1; ATF7IP; BCL6; DLX5; ZNF711; ZNF148; HOXB13; FOXA1; BBX; MED13; HOXD1; SOX10; TRIB3; HOXB6; ZNF224; REPIN1; SMARCA1; BRD4; ZNF415; TBX3; BASP1; RBL2; TCF4; FOXF1; ZNF44; ZNF304; MED24; BNC2; SSX1; NKX2-1; HIC2; GATA6; SIX2; ARNT2; TFAP2C; ZNF516; ZBTB20; ZNF264; NR3C1; FOXF2; BCL11A; KDM5B; TRIM16; TOX3; RORA; MYRF; HTATIP2; GLI2; SOX11; ZIC1; ARID5B; ZNF652; KLF5; SSBP2; KDM5A; MSX1; MEF2C; CRYM; PEG3; STAT5B
Down-regulation 139 FOSL1; CCNA2; MYBL2; RUVBL1; MYC; NUP62; HMGA2; PSMC3IP; TFDP1; PMS1; TCERG1; NPM1; TAF1A; SFPQ; ADRB2; FOXM1; PPRC1; HNRNPD; CBFB; C1QBP; PA2G4; RNF138; HMGB1; SUV39H1; SF1; EGR1; RBL1; TBP; SSRP1; BRCA1; ZNF200; BLM; ORC2; GCFC2; CENPF; WDHD1; ZBTB18; BAZ1A; DR1; PARP1; RAN; GTF3A; TAF9; MYBBP1A; HMGA1; KLF6; SNW1; WHSC1; SMARCE1; MLX; RBM14; THAP1; TBL1XR1; GABPB1; SMARCC1; NFIB; HMGB2; ZNF22; AATF; ZNF593; BIRC2; YEATS4; URI1; DNAJC2; ZMYM2; TFAM; PQBP1; ELK3; CEBPG; RBM39; RNF6; YWHAB; ITGB3BP; CNBP; KLF2; EZH2; SAP30; ZNF281; MAFF; XRCC6; CBX3; BCLAF1; SAFB2; PRKDC; CBX5; ING3; KMT5A; GATAD2A; RB1; SMAD1; ENY2; RBBP4; ERG; ETV1; CEBPZ; CCNH; CTNNB1; TSC22D2; ZNF146; NFYB; WWC1; ZNF232; CHD7; RNF4; EDF1; HOXC4; EGR3; TAF1D; PREB; RUVBL2; USP22; HES1; CRY1; CALR; YBX1; AHR; E2F3; IFI16; APEX1; PURA; ZNF131; MAFB; JUN; HOXC6; SMARCA2; PSIP1; HOXC10; ASCL1; PPARGC1A; FOSB; ELF1; MTF2; DMTF1; HHEX; IRX5; AEBP1; FOS; ID1; ESR1