Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17300	Withaferin-a	GSE70138	MCF10A	Human	24h	10uM	EID0019

Response Information :

Types	Number	Response transcription factors
Up-regulation	81	EGR1; NR4A1; PPARD; RELB; ATF3; CALCOCO1; CBX4; KLF4; SOX4; ZFHX3; LMCD1; ID3; NFIC; HMGA2; ZNF423; JUN; CBX7; DLX5; JUNB; FOSB; IRF9; EGR2; CDX1; ATF4; CITED2; FOS; NKX2-1; GTF2IRD1; HEY1; DDIT3; TLE2; ZNF532; DLX2; NRBF2; CUX2; HOXD1; JUP; JUND; SOX9; HMGN3; CREB3L1; TGFB1I1; SMAD3; TRIB3; CDIP1; MEIS2; FOSL2; TP63; ZFPM2; ST18; TCF7L1; ZFP36L1; ID1; SOX2; FOXF2; CBFA2T3; NR4A2; ZBED2; IRF7; ARNT2; ERBB2; IRF4; MSX1; KLF11; BTG1; MNDA; SOX17; FOXG1; ZSCAN18; IRF6; GATA6; LOXL2; PTRF; BCL6; POU2AF1; MAFB; TSC22D1; FOXF1; SNAI2; BASP1; MEF2C
Down-regulation	114	MYC; CCNA2; NRIP1; NFKBIA; ADRB2; CRK; PBRM1; CENPF; FOXO3; ATF1; PRKDC; RUVBL1; NFIL3; CNOT1; BAZ1A; ZBTB11; RFX7; HOXA5; HDAC2; KAT6A; RB1; PAXBP1; RAD21; TAF4; BTAF1; PURA; ZNF12; ZNF146; ZMYND11; URI1; MED13; RFC1; PBX3; GTF2I; SMAD1; BMI1; CNOT6; SMAD5; MED23; ZKSCAN1; ZMYM2; ZNF443; HES1; AFF1; BCLAF1; RNF6; ZNF107; MTDH; MYB; BRIP1; CLOCK; KMT2A; SUZ12; IKBKAP; HIPK3; ORC2; SP3; ZNF292; CBFB; MKL2; ZNF148; ADNP; CHD9; MGA; DNMT3B; TBL1XR1; FUBP1; COPS2; PMS1; RBBP4; CCNC; ZNF217; TRPS1; ZNF189; TAF1D; NFAT5; CDK8; DEK; MYBL1; NFIB; HDAC4; SIX1; WWTR1; ZNF551; HMGB3; E2F3; ERG; NR1D2; ZNF430; FOXC1; ARID1A; SAP30; ZNF160; ELK3; AHR; HLTF; HMGB2; CHD7; HOXB2; TOX3; MYRF; HOXB6; ARID4B; ZBTB18; TBL1X; NR2F2; HOXC10; MYT1L; ZNF91; HOXC6; STAT5B; NR3C1; SATB1; PEG3