Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17298	Mitoxantrone	GSE70138	MCF10A	Human	24h	0.12uM	EID0019

Response Information :

Types	Number	Response transcription factors
Up-regulation	107	CBX4; CALCOCO1; EZH1; MEIS2; CREG1; ING4; PPP1R13L; PRDM2; ZBTB44; SREBF2; DBP; TP63; KAT2B; HOXB5; ZNF768; CBX7; JUNB; MED13; NR1H2; MEIS1; MZF1; ZNF337; ZNF223; NFE2L1; SUPT4H1; PLAGL1; HOXB13; FOXJ3; ZSCAN32; CITED1; ZKSCAN1; CSDC2; IRF4; TRIM22; HDAC9; SSX3; USP21; CD3D; HBP1; CLOCK; AES; SIN3B; ZNF224; SIAH2; SSX1; CITED2; PCGF2; IKBKAP; MAGED1; ZNF83; SERTAD2; NFE2L3; PNRC1; BCL11A; ZNF611; TCF4; ZKSCAN7; ZNF133; TRIM16; PHOX2B; SMARCC2; ZNF394; RORA; KLF4; BTG1; GATA6; MXI1; MEOX2; BASP1; RUNX1; ZNF266; HAND1; WNT4; ZNF302; MYB; ZEB2; RUNX3; HOXB7; GRHL2; IRF8; CUX1; IRF9; HOXB6; MED24; SHOX2; ZNF652; TOB1; FOXA2; IFI16; MNDA; PDLIM1; ZNF160; PIR; ZNF43; NEUROD1; DLX5; HOXB2; CREB1; BCL6; SMARCA1; CTBP2; PAX6; POU2AF1; ZNF91; ZNF264; GATA3; TBX3
Down-regulation	106	CBFB; CCNA2; CENPF; FOXM1; NFIB; SFPQ; GABPA; NPM1; RNF138; HMGB1; CHD4; SSRP1; NUP62; PA2G4; ZNF217; TCEA1; HNRNPD; TFAM; XRCC6; UBE2I; SMARCE1; MYBL2; RBM14; HMGB3; IKZF5; CTCF; BRD3; TFDP1; YEATS4; HDGF; SP3; HSBP1; TEAD4; BRD2; AGO2; ENY2; USP22; HMGB2; CNOT1; ATF1; CCNC; TGIF2; ID3; MTDH; TCF3; SF1; HMGA2; NKX2-2; TBPL1; RBBP8; E2F3; KLF6; PQBP1; TAF9B; SFMBT1; UBE2B; ILF2; HDAC1; ELF1; CNBP; CHD7; PTTG1; RAN; CCNH; LYL1; ARL2BP; SMARCC1; RBM39; XBP1; PTRF; SMAD2; DEK; ZNF165; FUBP1; RBBP4; ASH2L; KLF10; WWTR1; ARID4B; TAF10; HEY2; AEBP1; CBX3; BRCA1; PSIP1; MTF2; RYBP; ZSCAN18; APEX1; EGR2; KLF5; POU4F1; TGIF1; RBL2; MYBL1; NR2F6; ID1; AHR; SAP30; ZFP36L1; NR2F1; HMGA1; ELK3; PEG3; SSBP2; FOS