Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17295	Mitoxantrone	GSE70138	MCF10A	Human	24h	3.33uM	EID0019

Response Information :

Types	Number	Response transcription factors
Up-regulation	116	TRIM22; CALCOCO1; NFKBIA; SOX4; AES; RELB; TSC22D3; ZMYM2; PBXIP1; IRF9; PNRC1; PBX1; STAT1; PHF1; RNF10; SRCAP; TFAP2A; IRF1; CREBL2; NCOA2; SUPT4H1; IRF6; CAMTA2; HBP1; BRD2; MAF; SOX15; HDAC5; FOSL2; INSM1; ZNF83; DDX5; CERS4; ING4; BAZ2B; MAFF; BTG1; ZBED2; LPIN2; MEIS1; KLF11; FOXN3; TFEC; ZNF532; ERBB4; ATF3; MNT; BCL3; ZNF415; SREBF1; ZBTB16; CHD9; TRIM16; TBX3; CNBP; TP63; JUN; CBX7; HIVEP1; DDX17; HOXD1; MXD4; SMARCA1; DRAP1; ZBED1; NFE2L1; ZNF665; NR1H2; DMTF1; IRF7; ZNF281; PLAGL1; ZBTB20; BASP1; DACH1; TOB1; NR4A2; TSG101; TCF12; ZNF302; ZNF611; EDF1; ZIC3; NR2C1; SMAD3; NR1H3; SCAND1; ARNT2; TGIF1; BCL6; DLX5; RORA; CREM; NR1D2; HLF; ZNF160; KLF10; KDM5D; NEUROD1; ERBB2; KDM5B; RFX5; ZBTB38; MXI1; MED13; SNAI2; FOXO4; FOSB; KLF4; CRYM; ID1; ZFPM2; TCF4; TOX3; ESR1; PEG3
Down-regulation	113	MYBL2; FOXM1; CENPF; CDK2; VGLL4; CCNA2; PTTG1; PCBD1; CEBPD; CHAF1B; WDHD1; SSRP1; E2F1; DNMT1; SUV39H1; RBM14; CBFB; NPM1; BRCA1; EZH2; PA2G4; HMGB2; GMNN; TRRAP; BLM; NOC2L; CNOT6; RBL1; PSMC3IP; YEATS4; AGO2; TAF4; TEAD4; C1QBP; ENO1; SMAD1; TAF5; PURA; BAZ1B; ECD; TFDP1; RNF138; RUVBL2; WHSC1; AEBP1; TAF9B; TCEA1; E2F8; TFAM; SAP30; NFIB; ZNF107; PRKDC; HMGA2; RBPMS; NFIL3; VDR; MEIS2; HNRNPD; AATF; ADNP2; SPEN; SHOX2; SFPQ; GTF2I; GATAD2A; WWTR1; RHOA; SUB1; PSIP1; MYBL1; XBP1; CCNE1; HDAC1; PAX5; HOXC10; DNMT3B; BATF3; TCF7L2; HOXC4; HMGB1; LEF1; CBX5; FOXD1; CCNC; RB1; TRIM28; ELF5; CREB3L2; NR2F2; RBBP8; HOXB7; APEX1; PIR; CHD7; SERTAD2; LMCD1; HMGA1; HLTF; ZFP36L2; FOXC1; POU4F1; SIX2; HOXC6; MKL2; MSX1; PITX1; MAFB; POU2AF1; SATB2; TWIST1; NR2F1; STAT5B