Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17269	Torin-1	GSE70138	MCF10A	Human	24h	0.37uM	EID0019

Response Information :

Types	Number	Response transcription factors
Up-regulation	121	SOX4; CALCOCO1; NCOA3; HMGA2; HBP1; CREBL2; HOXD1; NAB2; PNRC1; ZNF117; FOXN3; CIR1; PBXIP1; ZNF354A; SP100; IRF9; ZNF12; MED12; YEATS2; PPP1R13L; BPTF; ZNF33B; HDAC5; TCEA2; ZNF623; PEX14; ELF4; HMBOX1; PCGF3; RELB; ID4; ZSCAN18; NFATC4; ZMYM2; HIVEP1; KAT2B; SRCAP; ZNF160; MNT; TCF12; ZNF224; SETDB1; ZNF337; PFDN5; ZNF688; MAML1; MXI1; CUX2; GTF2IRD1; ZNF83; ARNT2; ZNF611; JUP; SP110; E2F5; TGFB1I1; NFE2L1; TCF7L1; CHD9; CBX7; KLF7; CDIP1; ZNF573; TRIB3; SALL2; NRIP1; MEIS1; VPS72; ZNF133; TSG101; BAZ2B; ZNF665; ZBTB20; PDLIM1; SMAD6; ID3; HOXB2; SNAI2; PHIP; BCL11A; NAB1; MYCL; LMCD1; ZNF532; ERBB2; ZBED1; SUPT3H; KLF11; NKX2-1; INSM1; IRF7; NR4A2; TLE4; FOXF2; EHF; LOXL2; SPEN; RORA; KLF6; SMARCA1; IRF6; ZNF43; ZNF512B; AEBP1; ZKSCAN1; MAF; NFE2L3; TCF7L2; SATB1; BASP1; HLF; HTATIP2; CREB1; SOX11; SOX9; GATA6; ZNF423; KLF4; ZNF91; ID1; FOS
Down-regulation	81	CCNA2; MYBL2; MYCBP; NUP62; CDK2; RBBP7; SUV39H1; DNMT1; FOSL1; EZH2; RUVBL1; CHAF1B; FOXM1; GTF2A2; GMNN; RBM14; HSF2; RBL1; PA2G4; PIAS2; BCLAF1; SUB1; PSMC3IP; YEATS4; WDHD1; ATF5; NFKBIB; NR2F1; CNOT1; BIRC2; CCDC59; TFAM; NFIB; WDR77; TFDP1; GATAD2A; SAP30; ING3; LEF1; RNF14; EED; PTTG1; HLTF; SFPQ; CRY1; RUVBL2; CCNC; POU4F1; BRCA1; CEBPG; PIR; HDAC1; WWTR1; PAX5; HMGB2; CBFB; NR2F2; SUZ12; NR2E1; IRX5; TAF9B; SMAD5; SHOX2; BAZ1B; HES1; RBBP8; CTR9; HOXC6; BMI1; ING2; ASCL1; MAFB; NKX3-1; MTF2; KAT6B; PITX1; ZBTB18; SCAND1; PAX6; ESR1; GATA3