Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17266 Torin-1 GSE70138 MCF10A Human 24h 10uM EID0019
Types Number Response transcription factors
Up-regulation 115 SUV39H1; SOX4; TSC22D3; FHL2; HBP1; HOXA10; FOXO3; NCOA3; CALCOCO1; SRCAP; HOXD1; RELB; PNRC1; ELF4; REPIN1; PPP1R13L; HDAC5; EZH1; EP300; CREBL2; GTF2IRD1; ZNF358; HMGA2; CDX1; ING4; AES; MXI1; NR1H3; IRF6; BAZ2B; CBX7; CIR1; PRMT2; ZBTB16; TGFB1I1; MAFF; MED12; ELF3; TSG101; IRF9; SUPT4H1; TCF7L1; HOXB13; BTG1; NFE2L1; CBX4; JUP; BACH1; PAWR; ATOH1; NCOA4; INSM1; SP100; ATF4; MAF; TERF1; DLX4; KLF6; SNAI2; ZNF117; GFI1; TDP2; SOX13; PBXIP1; CITED2; CHD9; ZIC3; FOXN3; ERBB2; PHIP; CD3D; LMCD1; LIN28A; ZNF611; ATF3; MEOX1; ARNT2; TRIM22; ZHX2; TGIF1; ZBTB20; GLI2; PRRX1; TP63; TSC22D1; TLE2; MYCL; ERBB4; KLF4; POU2AF1; EHF; NR1I2; ZNF160; TRIB3; TBX3; SSBP3; ST18; DMTF1; GATA6; JUND; TRIM29; SOX9; KLF5; HDAC9; LITAF; KDM5B; ZNF91; HTATIP2; FOXO1; SATB2; BCL11A; ZIC1; FOSB; ZNF423; FOXO4
Down-regulation 94 MYCBP; MYBL2; FOSL1; DNMT1; RUVBL1; CCNA2; PARP1; NUP62; GMNN; CDK2; EED; SSRP1; GTF2A2; WDR77; PRKDC; RBM14; SNIP1; TFAM; HDAC2; C1QBP; EZH2; WDHD1; DR1; RUVBL2; PSMC3IP; TAF9B; EGR1; RNF138; MED6; UBE2L3; GTF2I; HOXB2; HOXA5; ATF5; CBFB; WWTR1; TFDP1; HNRNPD; ZNF200; PA2G4; BAZ1A; NFIB; YEATS4; FOXM1; BCLAF1; TAF9; WWC1; SFPQ; WHSC1; RBBP8; CEBPG; HOXB6; XRCC6; GATAD2A; SMAD5; CEBPZ; CRY1; HSF2; HMGB1; SMARCA4; TRIM28; SMAD1; TEAD4; IKBKAP; ILF2; HLTF; SMARCD2; BRCA1; FUBP1; CTR9; HEY2; PBX3; LEF1; MEIS2; IRX5; PITX1; HMGB2; CHD7; HOXB7; ETV1; PURA; KLF10; ZNF331; ING2; MEIS1; HHEX; FOXC1; SUB1; MKL2; TBL1X; PEG3; NR2F1; WT1; ID1