Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17240 Azd-7762 GSE70138 MCF10A Human 24h 0.12uM EID0019
Types Number Response transcription factors
Up-regulation 18 TSC22D3; RFX5; HMGN3; NKX2-1; CITED2; INSM1; ZBTB18; CRYM; ID3; HMGB2; THAP11; NR2F1; HOXB6; NR4A2; NR2F2; ID1; ELK3; SATB1
Down-regulation 29 IKBKAP; CREG1; CEBPB; TGFB1I1; SOX9; HEY2; HIVEP1; BHLHE40; DLX5; PITX1; RXRA; FLNA; SMAD3; SATB2; NKX3-1; KLF4; TRIM29; TBL1X; ZNF91; SCAND1; ZEB2; MNDA; SNAI2; HLF; SSX1; MAFB; ZNF264; LEF1; IKZF1