Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17226 Wz-4-145 GSE70138 MCF10A Human 24h 10uM EID0019
Types Number Response transcription factors
Up-regulation 198 TSC22D3; CALCOCO1; FOXO3; TLE1; SREBF2; PBXIP1; ELF3; NCOA3; JUP; PNRC1; NFKBIA; HBP1; NFE2L1; TRIM22; IRF9; TP53; FOXN3; FOSL2; HDAC5; TFAP2A; IRF6; CREG1; TRIM29; BTG1; ING4; SRCAP; CERS4; CBX7; CITED2; ELF4; ZNF665; BAZ2B; ZNF117; HMGN3; ZMYM2; ZNF688; PHF1; ARNT; SP2; ID2; ZKSCAN4; BPTF; CIR1; SALL2; TRIM16; NCOA2; ZNF12; MED12; ATF3; ZNF611; CREBL2; PSPC1; EZH1; TFEC; ERBB4; ZKSCAN1; SUPT4H1; TRAK1; STAT6; MEIS1; CEBPD; HINFP; ZNF124; ZNF358; RING1; CARF; MZF1; ZNF217; STAT2; MYCL; STAT1; SOX3; KDM4A; HIPK1; PRDM2; KAT2B; ZNF175; HMG20A; VGLL4; NAB2; AES; ZHX2; MITF; ZSCAN31; GATA6; ZNF91; CSDC2; NFYC; TFAP2C; BCL6; MED13; ETS2; TGIF1; IRF7; TP63; TCF7L1; ZNF83; RORC; ZNF44; OSR2; MKL1; ZNF189; RARG; BNC2; RCOR1; MDM2; DLX4; ERBB2; KAT7; CARHSP1; RXRA; EPAS1; WNT4; CTNNB1; TEAD3; ZMIZ2; MYRF; SETDB1; ZNF532; BHLHE40; SP140L; PPP1R13L; TCEB2; TCF25; KLF11; NRBF2; PDLIM1; ZNF160; PCGF2; KLF5; PIR; ZNF292; NFIL3; PCGF3; SOX13; PBX1; SP100; ZNF33B; ZNF467; ZNF652; NAB1; MAF; SMARCC2; ZNF426; YAP1; CUX1; DDIT3; TSG101; ZSCAN18; SMAD6; TXNIP; BACH1; HDAC6; MXI1; ARID5B; RFX5; TLE2; SP110; HOXD1; REPIN1; PHIP; ZNF580; MEIS2; TCF7L2; ZNF304; BCL11A; JAK2; HOXA5; ZNF264; IRF1; ZNF331; PAWR; GRHL2; ZNF468; ZBTB20; SSBP3; KAT6B; BASP1; ARNT2; MNDA; ZNF512B; HLF; BCL3; TOX3; REL; TAL1; HDAC9; INSR; SCAND1; ARID4B; MYB; DMTF1; HTATIP2; FOXO4; MAFB; KDM5B; WT1; FOS
Down-regulation 145 CCNA2; FOSL1; MYCBP; MYBL2; RUVBL1; MYC; FOXM1; PARP1; PUF60; PA2G4; DNMT1; HMGA2; EGR1; TCERG1; CBFB; SSRP1; CENPF; C1QBP; CDK2; RUVBL2; SUV39H1; E2F1; BRPF1; CHAF1B; MYBBP1A; PTTG1; WHSC1; RBL1; NOC2L; EZH2; PPRC1; NPM1; RNF138; ETV4; GABPB1; NUP62; KMT5A; GMNN; HMGB1; NKX2-2; TAF1A; BCLAF1; WDHD1; CAPN15; PMS1; EGR3; DRAP1; BAZ1A; PSMC3IP; EGR4; GCFC2; TAF5; XBP1; HNRNPD; TAF9; SMAD1; MED27; POU3F2; ZNF473; SFPQ; GTF2A2; POLR3F; TFAM; AGO2; HDGF; ZEB1; WWTR1; TBP; WDR77; NFIB; HHEX; DNAJC2; BRCA1; TFDP1; ZNF22; YWHAB; ITGB3BP; EED; YAF2; AATF; ING3; ILF2; CARM1; CEBPZ; IKZF5; ETV1; PURA; NR2E1; HMGB2; ETS1; HMGA1; SMARCA4; ETV5; MEOX2; TRIM28; PRKDC; BLM; ZNF281; CBX6; MLXIP; SFMBT1; DEK; CCNE1; RBM14; ECD; KLF7; CHD7; EGR2; RAN; TEAD4; CRY1; ELK3; PREB; PAX5; HLTF; ING2; NR2F1; BATF3; IKBKAP; ZNF239; RBBP7; MSX1; LEF1; SHOX2; CALR; SMAD3; POU4F1; TAF9B; NR2F6; HOXB7; PLAGL2; MYBL1; PITX1; DLX2; FOXG1; BCL11B; MYT1L; KLF2; SAP30; SATB2; ZBTB18; TBL1X; SOX11; PPARG; SATB1