Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17221	Azd-5438	GSE70138	MCF10A	Human	24h	3.33uM	EID0019

Response Information :

Types	Number	Response transcription factors
Up-regulation	77	TSC22D3; NFKBIA; FOXO3; ZNF629; TCEA2; TLE1; ELF3; RXRA; ESRRA; ZNF12; AR; SETDB1; NFKB2; IRF6; RELB; PRDM2; TRIM16; ZNF83; VGLL4; EMX2; ZNF23; PCGF1; MEN1; MSC; CERS4; KLF4; DBP; SRCAP; ZBTB17; PCGF2; SPEN; TADA3; TERF2; HEY1; KAT8; ZNF133; KLF10; ZNF91; CCNE1; ZKSCAN1; BHLHE40; WWC1; KDM5D; PBX1; RLF; IRF8; SHOX2; BCL6; ATF7IP; OVOL2; DACH1; TRIP6; RUNX3; HIRA; NKX2-1; ZNF304; NR1H2; BRD4; KLF11; MECOM; ZNF274; SIAH2; ZNF512B; MEIS1; ARNT2; ZNF264; MXI1; CREB1; BASP1; PAX6; MAFB; BCL11A; FOXG1; FOSB; SOX11; ESR1; FOS
Down-regulation	88	CCNA2; ATF1; SFPQ; BCLAF1; CENPF; SMARCC1; EGR1; MED7; HMGA2; FOXM1; ATF5; ADRB2; YEATS4; WDHD1; MNAT1; VEZF1; SAFB2; BRD8; PDLIM1; ZBTB1; TFDP1; RAD21; C1D; ETV1; HMGB2; ETS1; RBBP4; HOXC4; RB1; SAP30; HOXC6; CBFB; MED14; DDX5; PBX3; RBBP7; TBL1XR1; MYBL2; BRCA1; AGO2; WWTR1; HMGA1; HNRNPD; HOXA1; ELF1; TAF9B; KLF2; DEK; LOXL2; BIRC2; RAN; YWHAB; UBE2B; C1QBP; NFIB; CTNNB1; TERF1; CBX3; HMGB1; HOXC10; PTTG1; MTDH; SUB1; PHIP; SMAD6; HHEX; PEG3; DNMT3B; HMGB3; BMI1; POU4F1; NR3C2; TBL1X; ID2; AEBP1; SMARCA1; TGIF1; ZNF721; TBX3; ID3; KAT6B; ELK3; DLX2; LITAF; IFI16; ZFPM2; SATB1; ZNF586