Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17201	Canertinib	GSE70138	MCF10A	Human	24h	0.12uM	EID0019

Response Information :

Types	Number	Response transcription factors
Up-regulation	145	TSC22D3; FOXO3; ZMIZ1; NFKBIA; CREG1; TLE1; CALCOCO1; PNRC1; BTG1; ELF3; MEIS1; PBXIP1; TRIM22; ZMYM2; NFE2L1; TP53; ZBTB1; ID2; NFE2L2; BPTF; BAZ2B; ING4; LDB1; SREBF2; TRIM29; HBP1; ESRRA; AES; ZMYND8; COPS2; ADRB2; IRF6; IRF1; SRCAP; PIR; OSR2; HDAC5; NFIL3; TRAK1; MZF1; REPIN1; HMGN3; FOXN3; ZZZ3; ZNF268; TOB1; TCF12; IRF9; MNT; ZNF652; KAT2B; STAT6; NCOA2; CBX7; CREBL2; RARB; ZNF83; FOSL2; RFX5; MYCN; HOXB5; MXI1; CEBPA; WNT4; MAF; ZNF688; FOXJ1; BBX; ZKSCAN1; ZNF665; ZNF611; DBP; TCEB2; PDLIM1; VGLL4; ZSCAN31; HIPK1; ZNF160; DDX17; DDIT3; MXD4; PEX2; PBX1; MECOM; ID3; STAT3; JUP; KLF10; MITF; ZKSCAN7; TRPS1; NAB1; FOXO1; CUX1; ZNF536; STAT1; TXNIP; ZNF44; CREB3L2; E2F5; TRIM24; KAT6B; TRIM16; MYRF; HOXB2; NR1H2; KLF11; ZBTB16; ZFP36L2; ID1; HOXB6; CITED2; POU2AF1; ELF1; EMX2; HDAC9; RYBP; ERBB2; ZNF468; PHF20; NR1D2; TP63; ZNF331; ARID5B; ZNF721; BCL11A; SIAH2; INSR; SNAI2; HEY1; BCL6; TOX; ZNF264; ZIC1; SCAND1; GATA6; CRYM; KLF5; NR2F2; FOXO4; SSBP2; ZNF91; GLI2; ESR1; DACH1
Down-regulation	94	CCNA2; FOSL1; MYBL2; FOXM1; HMGA2; CEBPD; CDK2; DNMT1; TCERG1; GMNN; CENPF; SUV39H1; FHL2; WHSC1; SSRP1; ETV4; CHAF1B; RBL1; YEATS4; RUVBL1; TEAD4; TAF1A; KMT5A; EZH2; E2F1; WDHD1; HMGB2; MYBL1; NOC2L; HMGB1; DRAP1; PSMC3IP; BRCA1; RBM14; PA2G4; HHEX; ZEB1; CBFB; TTF1; PTTG1; NFIB; ETV5; PSMC3; UBE2I; TFAM; CAPN15; BRCA2; EGR1; GABPB1; DEK; ILF2; HMGA1; PRKDC; LZTS1; CBX5; CEBPG; HNRNPD; PBX3; BLM; TAF5; BRIP1; MTF2; TAF9B; ETV1; HOXA1; E2F8; CALR; RNF138; SLC2A4RG; SOX9; TGFB1; BATF3; BCLAF1; NPM1; CCNE1; KLF6; BAZ1B; RB1; YWHAB; WWTR1; TRIB3; ZBED2; TRIM28; RBBP8; SUB1; PTRF; SMAD1; HOXC10; NFE2L3; AEBP1; EGR3; SATB2; FOS; SATB1