Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17197 Canertinib GSE70138 MCF10A Human 24h 10uM EID0019
Types Number Response transcription factors
Up-regulation 284 TSC22D3; PBXIP1; IRF9; FOXN3; CALCOCO1; ING4; ZNF222; ATF4; PNRC1; ZNF268; TRIP11; RELB; ZKSCAN4; KDM4A; CERS4; ZNF112; TP53; BTG1; HOXB1; PRDM12; TFAP2A; HBP1; ZNF768; ZKSCAN3; JUP; KAT2B; HOXC5; CEBPD; ZNF225; ZNF223; EP300; ELF3; EYA1; VENTX; ZNF358; HDAC5; GCM1; ZNF75D; NR5A1; ZSCAN16; ZNF331; NFATC4; ZNF623; PAX8; SIRT2; SOX3; ZNF345; KLF4; TRIB3; ZNF180; MYNN; CXXC1; TSHZ2; NFKB2; DLX4; STAT2; BHLHE41; ZNF140; PIR; PRDM14; TBX1; DDIT3; CREBL2; ZNF136; EGR2; SOX4; VGLL1; NR1H4; MAF; NCOA2; ZNF235; SPI1; RARG; CREB5; SALL2; HMGN3; LHX3; ZNF175; ZBTB3; CBX7; ZSCAN9; ZNF354A; THAP7; HOXD1; SUPT7L; EMX2; ZNF778; THAP10; FOSL2; PHF1; CIR1; THRB; NR4A3; BARX1; RING1; ZNF606; KLF3; ZNF184; ZNF701; CHD2; NRBF2; GATA6; ZNF688; BNC2; RFX2; ZNF12; ZNF155; CARHSP1; ETV5; ELF4; SKIL; NFATC1; ZFHX3; PRDM2; DYRK1B; SOX2; ATF3; ZNF573; THAP11; ID4; ZNF665; HIPK1; PHIP; LMCD1; DDX17; CAMTA2; IRF7; SIX3; ZNF536; TCF25; NAB2; ZNF682; CBX4; NFYC; CSDC2; RORA; ZNF93; ZNF117; BRD2; ZNF423; ARNT2; ZNF33B; CIITA; ZNF227; TRIM16; PBX1; CBX2; OVOL1; PIAS4; MZF1; ZNF74; GBX1; RORC; TCF7; ZNF419; MITF; EN1; ZNF611; ZNF500; HINFP; ATN1; RARB; TRIM24; CEBPA; TWIST1; ZNF219; MKL1; BCL6; TP63; IRF1; MYRF; NR0B1; IRF6; ZHX2; ZNF14; ZNF91; DLX5; ZNF195; CITED2; ATOH1; OVOL2; ZNF224; CDIP1; ZNF85; TRIM29; SMAD6; CBFA2T3; HMBOX1; ZNF189; KLF2; MEIS2; TERF1; ELF5; FOXJ3; ZNF44; PFDN5; HEY1; GBX2; MYCL; DBP; NFE2L1; SP140L; NR5A2; SOX10; ZNF10; CREB3L1; TFEC; MSC; ZSCAN31; TBX21; JAK2; NPAS2; SOX13; ZNF177; SP110; HTATIP2; MEOX1; ZKSCAN1; ZNF232; ZNF32; STAT4; CREM; ZSCAN18; HDAC9; MXI1; TRIM22; NANOG; ZNF24; SIX2; JUND; ZNF160; LPIN2; ZIC1; SOX17; KAT6B; LITAF; EHF; ZNF43; KLF11; TOX; ZNF529; NFIX; INSM1; NR1H2; PAWR; MAFB; ZNF350; TCF7L1; ZNF415; ZFPM2; MAFF; POU2AF1; ARID5B; TCF4; ZNF264; TLE2; ZNF165; TXNIP; SHOX2; TLE4; STAT1; SPIB; TCF21; WT1; ID2; GLI2; MEIS1; FOXO1; EYA2; RUNX3; ZBTB20; ZEB2; PEG3; TOX3; OSR2; INSR; FOXO4; HLF; SOX11; FOS; CRYM; BCL11A; TBX2; MEF2C
Down-regulation 143 CCNA2; FOSL1; ADRB2; NRIP1; RUVBL1; MYCBP; MYC; MYBL2; PUF60; TCERG1; SUV39H1; NUP62; RBM14; HDAC2; PARP1; SSRP1; CENPF; EGR1; BRD3; HMGA2; NPM1; HMGB1; PTTG1; BCLAF1; PA2G4; UBP1; TFAM; CHD7; WDHD1; BAZ1A; CBFB; SMARCA4; CBX5; SFPQ; RRN3; C1QBP; CAPN15; RHOA; WHSC1; HNRNPD; CEBPZ; KLF7; BMI1; MTDH; UIMC1; NELFB; PSIP1; FOXM1; TBP; DEK; PRKDC; HMGB2; HOXA10; RUVBL2; EED; ECD; PMS1; TFDP1; EZH2; WDR77; UBE2I; REST; RFC1; HDGF; ZMYND11; YWHAB; SMARCA5; ELK3; MED4; DDX54; SMAD5; KMT2B; HES1; ITGB3BP; CCDC59; ZBTB18; JARID2; BLM; MLX; ORC2; BRCA1; BAZ1B; ETS1; ATF1; SPEN; RBBP7; PSMC3IP; PPRC1; CHD1; NCOA6; TRRAP; RBBP4; EDF1; AATF; NFIB; PMF1; SERTAD2; RNF4; SMAD1; NONO; ZEB1; HLTF; SMARCC1; CBX3; LEF1; DNMT3B; DRAP1; PLAGL2; SUB1; TBL1XR1; RBPMS; SF1; RB1; TBL1X; TAF9B; ABL1; CTR9; ZNF146; TEAD1; MTF2; AFF1; MLXIP; IRX5; TRIM28; TGFB1I1; ARID1A; CERS6; MKL2; MYT1L; KMT2A; RBL2; MED24; BHLHE40; ZBTB38; EGR3; HMGA1; NR2F2; FLNA; RBBP8; BASP1; NR2F1; STAT5B; SATB2