Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17196 Afatinib GSE70138 MCF10A Human 24h 0.04uM EID0019
Types Number Response transcription factors
Up-regulation 292 TSC22D3; FOXO3; ZNF268; CALCOCO1; ADRB2; ZMIZ1; MEIS1; NCOA3; ELF4; PNRC1; HDAC5; NFKBIA; TRIM22; ING4; HMBOX1; BPTF; SOX4; JUP; PBXIP1; ZSCAN9; HBP1; SALL2; ZNF12; KAT2B; ZNF84; EMX2; SOX17; SUPT7L; FOSL2; TLE1; EHF; ZNF768; ZNF345; NCOA2; ZBTB11; MYF5; PBX1; CEBPD; ZMYM2; ZBTB44; TFAP2A; ZNF354A; IRF9; NFE2L2; ZKSCAN4; CHD9; ZNF112; BRWD1; BTG1; HIPK1; HOXB3; CREG1; ZNF623; ZNF665; PCGF3; TRAK1; KAT2A; ZNF337; SCAI; E2F5; DLX5; TAF1C; PRDM4; RARG; ELF3; FOXN3; MYRF; SRCAP; EP300; HOXD1; ZNF124; NAB2; ZNF606; HIVEP1; ZNF136; ZNF33B; ZNF140; ID2; ZNF467; HOXB1; ZFHX3; KDM4A; NR0B2; ZNF629; ZNF667; ZNF235; SOX12; ZHX2; TRIM29; RING1; NFE2L1; KLF3; WNT4; ZNF75D; ZNF358; ZNF611; CIR1; CHD4; ARHGAP35; CBFA2T3; TCF25; ZNF512B; TCEA2; CARF; ZNF44; ZNF669; DLX4; ZNF223; MZF1; CERS4; ZIC1; ZNF34; NAB1; ESR2; ID4; ZNF195; SIM1; ZNF415; HOXB2; ZNF135; TFEC; MEF2D; HDAC9; MED23; TEAD3; ZNF500; TRPS1; SETDB1; BAZ2B; ARNT2; ZKSCAN7; MEN1; PRDM2; SMAD6; EZH1; MECOM; MNT; ZSCAN18; CBX7; MYCL; L3MBTL1; NR4A3; ZXDC; ZNF350; ZNF331; ZNF117; AES; ZNF160; BCL6; CIITA; TP63; ZNF304; ZFP36L2; ZNF257; DAXX; NFATC4; CUX2; HIC2; RUNX1; SP2; ZNF93; OVOL2; NFAT5; ZNF14; PRDM1; HSF1; FOXK2; ZBTB16; MEIS2; ARID5A; PHIP; RORC; NR1H2; ZKSCAN1; ZNF165; CBX4; SUPT4H1; CDYL; AR; CSDC2; TAF7; TCF4; INSM1; ZNF711; SIX3; ZNF3; COPS5; TCF7L1; TRIB3; ZNF83; KLF11; TAL1; MED12; REPIN1; GRHL2; PKNOX2; IRF6; BCL11A; DDX17; SP110; ZNF529; ZNF43; SMARCC2; IRF1; SP140L; OLIG2; ZNF419; ZNF423; ZSCAN31; ZNF394; KLF1; SNAI2; TLE4; KLF13; ZNF217; CHD8; MECP2; OSR2; ZNF85; BACH1; SP100; HIVEP2; CDIP1; MED13; TRIM16; ERBB2; ZNF468; ZNF133; ZNF239; ZMYND8; VGLL4; ZNF573; JAK2; ARID5B; ID1; ZNF426; BNC2; ZNF224; MNDA; THAP10; ATF3; FOXO1; MED17; SOX2; LMCD1; POU2AF1; NR2C1; ZNF91; ZFPM2; MITF; ERBB4; CEBPA; ZNF652; ZNF264; PLAGL1; PLAG1; TOB1; KLF9; TSC22D1; MEOX1; NR1D2; IRF7; ARID4B; WT1; FOXF2; MKL2; ETS2; PDLIM1; ST18; TXNIP; CUX1; BBX; REL; HEY1; TFAP2C; MYCN; GATA6; AHR; RFX5; TCF7L2; SSBP2; ESR1; PEG3; TWIST1; INSR; SPIB; FOXO4; IRF8; TOX3; BHLHE41; FOS; ZNF586
Down-regulation 98 CCNA2; FOSL1; MYBL2; FOXM1; NUP62; PTTG1; FHL2; CHAF1B; ABL1; SUV39H1; CENPF; MYCBP; CBFB; CDK2; HMGB2; HMGB1; HNRNPD; YEATS4; RBM14; EZH2; PSMC3IP; PA2G4; WDHD1; UBE2I; RBL1; RUVBL1; ENO1; SAP30; SMARCE1; BLM; BRCA1; DRAP1; NFKBIB; TFAM; GABPB1; NPM1; SSRP1; BCLAF1; DR1; NFIB; RUVBL2; XRCC6; KMT5A; WHSC1; BATF3; DNMT3B; RBPMS; BMI1; WWTR1; HMGA2; RBBP4; CCNH; PSMC3; NFKB1; PPRC1; PITX1; EDF1; SFPQ; TAF9B; ING2; SMAD1; ELK3; RNF138; ETV1; HHEX; RBBP7; AFF1; EGR3; ASH2L; NR2F1; BAZ1A; TBL1X; CALR; HOXC10; TRIM28; HMGA1; BAZ1B; HOXC6; HLTF; TFDP1; HOXC4; POU4F1; DEK; NR2F2; RBPJ; HMGB3; MED1; HOXB7; KLF6; SUB1; BHLHE40; SATB2; PBX3; SOX9; CITED2; KDM5D; BASP1; SATB1