Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17187	Celastrol	GSE70138	MCF10A	Human	24h	1.11uM	EID0019

Response Information :

Types	Number	Response transcription factors
Up-regulation	127	TSC22D3; NCOA3; PIR; PBXIP1; ELF3; DDIT3; ING4; ATF3; PBX1; NR0B1; TRIB3; ZSCAN16; FOSL2; CALCOCO1; PHF1; TDP2; TRIM16; FOXC1; ZNF358; KDM4A; TRIM27; ZSCAN31; ZNF768; TFAP2C; CHD9; TEAD3; CERS4; NFE2L1; MNT; CREB5; CIR1; SIM1; LMCD1; NFYC; RING1; SREBF1; CEBPA; TRIM29; ATF4; E2F3; ZNF117; NAB2; ELF5; HTATIP2; BATF; TCEB2; HOXD1; ZHX2; PNRC1; ZNF189; TP63; PIAS3; SMARCC2; SIN3B; ZNF623; SUPT4H1; SOX3; SMAD6; MITF; EZH1; ZXDC; TFEC; MZF1; ZNF580; CREB3L1; FOXE1; SOX10; NKX3-1; BCL6; MYCL; BHLHE41; ETV5; MAGED1; PHIP; THAP10; NR4A1; TBX3; ZNF83; MAFG; BTG1; HBP1; TFDP2; SIX1; GATA6; NPAS2; XBP1; BAZ2B; MXI1; ZNF93; ID2; SUPT3H; ZNF512B; JUND; ZBTB20; TOX3; NR1H4; NFATC1; IRF9; POU2AF1; NANOG; MECOM; BRD4; ARNT2; MED13; DNAJC1; ERBB4; SOX9; ZSCAN18; FOXF1; FOXG1; TSC22D1; ZNF516; MAFB; ID4; INSR; OSR2; CREM; SPIB; NR4A2; IRF7; TGIF1; KLF4; KDM5A; SSX1; BCL11A; PPARG; FOXO4
Down-regulation	135	CCNA2; MYBL2; RUVBL1; ADRB2; FOSL1; SSRP1; HMGB1; NFKBIA; CDK2; NUP62; NPM1; DNMT1; HDAC2; GMNN; SUV39H1; FOXM1; HMGA2; MED6; CENPF; MYC; CHD7; UBTF; SOX4; PTTG1; ING3; XRCC6; UBP1; NOC2L; MLXIP; SUB1; HDGF; ILF2; SMARCA4; BLM; HMGB2; RBM14; RBM39; WDHD1; WHSC1; ID3; RBL1; BCLAF1; PSMC3; RFC1; STAT3; RAN; PSIP1; TAF5; NONO; AEBP1; HES1; BMI1; TFAM; CCNT1; YEATS4; TAF1A; TEAD4; MYT1L; RNF138; CTBP1; NRIP1; EED; IKZF5; MYBL1; PSMC3IP; MYB; ZNF22; CTNNB1; HNRNPD; NFYB; ATF1; TFDP1; ETS1; SFPQ; TGIF2; SMAD1; KLF6; HIPK3; RUVBL2; PA2G4; CCNE1; ZBED4; TGFB1; ELK3; KLF7; KLF10; HOXA1; C1QBP; BAZ1B; PRKDC; JUNB; ZBED2; KLF9; RB1; EGR1; ZFP36L2; NKX2-2; ASXL1; JUN; PTRF; RHOA; CBX5; DEK; HOXB2; BRCA1; CUX2; YBX1; EGR3; IRF1; RNF4; BCL11B; CNBP; TRIM28; TFCP2; CBX3; MED24; MEOX2; HOXC4; BACH2; IRF4; ID1; HDAC9; HMGB3; HOXA5; SMAD7; MEIS1; FOXD1; APEX1; IFI16; PAX6; TXNIP; MSX1; LEF1; STAT5B; IKZF1