Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17166	Mk-2206	GSE70138	MCF10A	Human	24h	10uM	EID0019

Response Information :

Types	Number	Response transcription factors
Up-regulation	94	TSC22D3; SREBF2; SOX4; CALCOCO1; CREG1; ZNF358; ZMIZ1; NCOA3; FOXN3; PBXIP1; EGR1; HMGA2; MNT; ZNF217; TULP4; BPTF; NCOA2; MAF; NR4A1; HBP1; CREB3L2; PPP1R13L; CAMTA2; CITED2; ZBTB16; CREBL2; ZMYM2; RBPMS; RELB; CBX7; AES; STAT2; IRF6; CEBPD; TRIB3; MEN1; NFE2L1; HIVEP1; HOXD1; LMCD1; TCF7L1; SKI; NFAT5; TGFB1I1; CDIP1; ZNF117; IRF9; TSG101; HOXB2; BAZ2B; CHD9; BCL10; ZNF281; FOSL2; PNRC1; ETS2; PHF20; NKX2-1; BTG1; YAP1; KLF6; ZBED1; ATF3; POU2AF1; ZBED2; IRF7; KAT2B; ARNT2; ZNF532; BHLHE40; PAWR; MEIS2; ERBB2; GATA6; NPAS2; HTATIP2; KDM5B; TGIF1; ZSCAN18; INSR; JUP; RUNX1; WT1; AEBP1; TBX3; SNAI2; HDAC9; TCF4; ZNF91; TXNIP; BASP1; ARID5B; FOXO4; FOS
Down-regulation	85	CCNA2; TCERG1; MYCBP; RUVBL1; MYBL2; FOSL1; NRIP1; FOXM1; RBL1; PSMC3IP; SUV39H1; ZNF473; NPM1; C1QBP; YEATS4; WDHD1; EZH2; RUVBL2; CCDC59; GCFC2; RBM14; HMGB2; ING3; SMARCE1; ADRB2; RNF138; ITGB3BP; BCLAF1; PMS1; NKX2-2; PTTG1; SSRP1; SMAD1; WHSC1; DNAJC2; PA2G4; ORC2; HSF2; WWTR1; TAF5; TRIM28; CENPF; RBBP7; CEBPZ; EDF1; SLC2A4RG; HLTF; BRCA1; ECD; SFMBT1; PAXBP1; BIRC2; RAN; HNRNPD; CCNC; HMGB1; PIR; TAF9B; DNMT3B; ZNF22; SALL1; POU4F1; ZNF593; NKX3-1; MED1; PITX1; GATA4; ILF2; EYA2; KLF10; MSX1; IFI16; MECOM; PEG3; DLX5; HOXC10; PAX6; RBBP8; LEF1; SSX1; MYT1L; ID1; ESR1; SATB1; IKZF1