Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17161 Palbociclib GSE70138 MCF10A Human 24h 3.33uM EID0019
Types Number Response transcription factors
Up-regulation 58 NCOA3; SREBF1; TRIM22; KDM4C; PBXIP1; MEIS1; MXD4; ELF3; CALCOCO1; AR; ARID5A; KLF13; WWC1; HOXB2; NR0B1; POU2AF1; ZNF217; AFF1; NFE2; PGR; SKI; KLF10; LPIN2; SMARCA1; SND1; MAGED1; STAT6; DEAF1; EYA2; OVOL2; EGR3; IKZF1; TERF1; TFAP2C; JARID2; IL16; KLF2; RBPMS; ZMYND8; CREB3L1; ZNF415; ZSCAN31; ID3; ESR1; ERBB2; FOSB; CRYM; FOXA1; ZFP36L1; ZBTB38; MYT1L; TOX3; SPDEF; BASP1; LEF1; SCAND1; ELK3; KDM5D
Down-regulation 54 CCNA2; FOXM1; CENPF; GMNN; NRIP1; PTTG1; HMGB2; MYBL2; HEY1; TDP2; ITGB3BP; RAD21; CCNH; CCDC59; WHSC1; KMT5A; SAP30; TAF5; FUBP1; TCEA1; CITED1; TTF2; PSMC3IP; LMCD1; HSF2; GTF2IRD1; SMAD6; CEBPG; CEBPD; TEAD4; RNF138; GATAD2A; HES1; ING3; CDYL; BRCA1; TRIB3; TBL1XR1; ZNF331; DEK; PBX3; CEBPA; TCF21; NR1I2; ZHX2; CBX3; MAFB; HOXB7; JUND; HMGB3; DACH1; ZIC1; KLF4; SATB2