Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17160	Palbociclib	GSE70138	MCF10A	Human	24h	10uM	EID0019

Response Information :

Types	Number	Response transcription factors
Up-regulation	44	EGR2; NRBF2; ZNF112; ZZZ3; ZNF7; RFX5; NKX2-2; FOSL2; PBXIP1; CUX2; PHF20; MAF; ZNF226; MNT; AFF1; HOXB2; ZNF189; BBX; LPIN2; MAGED1; NR1H2; ZNF573; SMAD2; MEIS1; NR0B1; STAT1; SMAD3; NFIB; PBX1; TCF7L1; RORA; MXI1; SIAH2; HOXC6; PEG3; HDAC9; ZBTB38; GATA3; ELK3; HTATIP2; FOS; CRYM; GATA6; BHLHE41
Down-regulation	86	CCNA2; MYBL2; FOXM1; GMNN; TP53; CEBPD; HMGB1; DNMT1; PSMC3; HMGB2; WDHD1; CENPF; CDK2; CHAF1B; RBM14; FOSL1; E2F8; YEATS4; ETV4; MED6; WHSC1; TEAD4; YBX3; EZH2; NFYC; KMT5A; EMX2; BAZ1B; CCDC59; PAX5; RAD21; TTF2; HSF2; SSRP1; MED4; BRD7; CNOT6; BLM; SMARCD3; BRCA1; XRCC6; ZNF107; PAXBP1; SMAD6; ZNF273; RAN; FUBP1; GTF3A; CCNE1; ING3; ZHX2; SMARCC2; CBX5; SLC2A4RG; PQBP1; HIC2; NR2F1; AEBP1; KLF5; ZMYND8; MNDA; ZNF331; FOXL2; PTTG1; POU2AF1; PITX1; PURA; RBBP8; MSX1; SIX2; ZEB1; FOXF2; FOXF1; FOXA2; FOXD1; TRIM29; BCL11A; TXNIP; ZBTB18; SATB1; ID1; LEF1; SATB2; KDM5D; IKZF1; ZNF586