Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17157 Osi-027 GSE70138 MCF10A Human 24h 0.37uM EID0019
Types Number Response transcription factors
Up-regulation 65 ZNF589; SOX4; ZNF112; HMGA2; HMBOX1; NAB1; ZBTB1; MNT; RBPMS; CALCOCO1; ZNF117; CUX2; HBP1; PRMT2; SIM2; WWP1; ZMYND8; PPP1R13L; PBXIP1; SALL2; EGR1; KLF6; MYBL2; TCF7L1; JUP; DDX17; PBX1; TGFB1I1; SMAD2; PNRC1; MEOX2; FOSL2; FOXD1; MAFF; SMAD3; CBX7; ID3; PDLIM1; IRF7; MEIS1; HES1; ATF3; IRF9; NANOG; TLE4; ERBB2; ELK3; NR1D2; MEOX1; EGR3; BHLHE41; DMTF1; HOXB2; KLF9; EGR2; KLF2; FOXG1; FOSB; ID4; ZNF423; EYA2; SCAND1; ZFPM2; TBX3; FOS
Down-regulation 28 CDK2; CCNA2; FOXM1; CEBPG; PRKDC; WHSC1; GATAD2A; HMGB2; C1QBP; CCNC; CALR; PBX3; TAF5; FUBP1; SFPQ; SUV39H1; NFIL3; CENPF; TOB1; EZH2; VDR; ILF2; ERBB4; TRIB3; RBBP8; MNDA; SATB1; PEG3