Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17155	Osi-027	GSE70138	MCF10A	Human	24h	3.33uM	EID0019

Response Information :

Types	Number	Response transcription factors
Up-regulation	130	PPARD; SOX4; TSC22D3; FOXJ3; CALCOCO1; RELB; CREBL2; FOXN3; MAFF; PBXIP1; HBP1; ING4; MNT; HOXD1; TCF12; AHR; ST18; HMGA2; STAT6; ZNF33B; MECOM; EZH1; BPTF; ZSCAN9; PEX14; AFF1; BAZ2B; POU2F2; NFKB2; ZNF83; MEIS1; MEOX2; HMBOX1; SOX15; ZNF175; ZNF354A; CDK7; ZEB1; MYT1; AES; SOX17; ELF3; ERBB4; SPI1; KLF3; DDX5; HOXD3; KLF7; INSM1; EBF2; ZNF189; MED12; ZNF93; SP110; ZNF606; PHF1; TRIM22; EGR1; MZF1; PNRC1; FOSL2; RUNX1; ERBB2; IRF7; LYL1; NCOR2; ZNF160; NR4A1; ZIC1; ZNF423; ZMYND8; NRIP1; ATF4; CHD9; NR2C1; SP100; LMCD1; HIVEP1; NEUROD1; KLF10; WWC1; DLX4; TBX3; BASP1; TGFB1; TAL1; ZNF415; ZBTB20; ZNF532; JUNB; NHLH2; HEY1; TRIM24; WNT4; TSG101; NKX2-1; MED13; BTG1; EGR2; PDLIM1; ELK3; HLX; TWIST1; ZFPM2; SUPT3H; TGFB1I1; TFDP2; NR4A2; PHF20; KLF2; ZSCAN18; SOX9; SNAI2; ARNT2; APEX1; IRF6; FOSB; MYRF; BCL3; JUND; ID4; MAF; FOXD1; TCF4; ATF3; FOS; DACH1; CREB1; SATB1; CRYM
Down-regulation	87	MYBL2; CCNA2; MYCBP; FOXM1; RUVBL1; CDK2; GMNN; NUP62; DNMT1; FOSL1; GTF2A2; TFAM; NOC2L; SUV39H1; EZH2; HMGB1; NFYA; ITGB3BP; PTTG1; RBM14; ABT1; HMGB2; CEBPG; PITX1; ZNF232; PA2G4; DR1; TGS1; ZNF107; PAX5; WDR77; CBFB; IKZF5; SAP30; RBBP7; ZNF184; GATAD2A; UBE3A; HOXC10; XRCC6; YEATS4; NELFB; BAZ1A; ZNF273; RUVBL2; BATF3; CALR; TFDP1; ZBED4; TAF5; MYBL1; BLM; CCNC; GTF2I; MED21; C1QBP; TEAD4; VPS72; STAT3; RNF138; CREBZF; SMAD5; SIX2; BRCA1; SUZ12; STAT1; PRKDC; HOXB6; POU2AF1; CTR9; SUB1; PBX3; MYB; BMI1; KLF9; SMAD1; HLTF; ING2; LEF1; ID3; RBBP8; TBL1X; ID2; SATB2; WT1; HOXC6; IKZF1