Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID17154	Osi-027	GSE70138	MCF10A	Human	24h	10uM	EID0019

Response Information :

Types	Number	Response transcription factors
Up-regulation	122	TSC22D3; FOXO3; FHL2; HBP1; SOX4; ELF4; NFKB2; ZNF358; PHF1; MNT; HOXD1; HMGA2; MAFF; EGR1; PNRC1; ING4; CREBL2; CALCOCO1; TCF25; SRCAP; TCEB2; SP110; PPP1R13L; NFE2L1; CERS4; ZNF217; BTF3; UBE2B; PRRX2; ZNF354A; TFAP2C; ZNF688; CDK7; FOSL2; PHF20; SP100; HDAC5; CHD9; BAZ2B; ELF3; TCEA2; MED12; BCL10; NKX2-1; DDX17; KDM5B; MEOX2; IRF9; TSG101; ZNF160; ZNF33B; NCOR2; KLF2; ZBTB16; PBXIP1; KLF3; ZMYND8; KLF11; ZNF93; ZNF611; PFDN5; TBX1; ERBB2; ZNF117; TRIM22; CARHSP1; NFAT5; NR4A1; ZNF83; TCF12; SALL2; IRF7; JUP; YAP1; NR2C1; SMAD3; HDAC9; TAF10; BACH1; TGFB1I1; DLX4; PDLIM1; IRF6; JUND; ZNF423; NFE2L3; ZEB1; DMTF1; CITED2; PRRX1; PTRF; TLE4; SOX17; ZFP36L2; ARNT2; TWIST1; ZKSCAN1; TRIM16; ST18; ERBB4; SSBP3; BCL3; BHLHE41; AHR; TSC22D1; EGR2; ZNF721; INSM1; MAF; ZBTB20; HTATIP2; TXNIP; TOX; TRIM29; LITAF; ZFPM2; SNAI2; NR4A2; BASP1; ATF3; ESR1; FOS
Down-regulation	83	MYBL2; MYCBP; CREG1; CCNA2; CDK2; TCERG1; GMNN; RUVBL1; FOXM1; DNMT1; RBM14; E2F1; SUV39H1; EZH2; EED; GTF2A2; YEATS4; NUP62; CEBPG; HOXA5; FOSL1; C1QBP; BLM; HMGB1; CHAF1B; CBFB; PAX5; WDR77; BRCA1; TOB1; ZNF107; DR1; SSRP1; CCNE1; HMGB2; TFAM; CBX6; PSMC3IP; HOXA1; BCLAF1; UBE2L3; RBBP7; ING3; RNF6; ZNF232; MEIS2; TFDP1; PURA; SFPQ; BAZ1A; ITGB3BP; TAF5; XRCC6; CCNC; SMARCA4; PA2G4; RAN; CBX5; LEF1; RNF138; RUVBL2; MLXIP; SAP30; MYB; CALR; DEK; PLAGL2; ILF2; SUB1; PITX1; IRF4; POU4F1; WWTR1; PBX3; HLTF; RFX5; MEIS1; PAX6; NR2F1; FOXF1; WT1; SATB1; IKZF1