Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17125 Fostamatinib GSE70138 MCF10A Human 24h 3.33uM EID0019
Types Number Response transcription factors
Up-regulation 51 POU4F1; EGR1; TAF7; TOB1; TERF2; NKX3-1; ZNF423; PFDN5; MAFB; SMAD6; ZEB2; TCF4; LYL1; ELK3; ZNF302; ST18; NFIB; ZIC1; BASP1; YWHAB; MECOM; TFEC; NR1H3; HBP1; ZNF24; CRYM; CBFA2T3; POU2AF1; ZNF512B; NHLH2; DLX5; PRRX1; SMAD7; LOXL2; JUNB; DACH1; WWTR1; HOXA5; EYA2; MNDA; TOX; SOX9; HMGA1; TRPS1; ESR1; IFI16; DLX2; THAP11; ID1; NR2F2; BHLHE41
Down-regulation 35 IKBKAP; ADRB2; HSF2; CENPF; PTTG1; SOX13; NR4A3; ASCL1; PBX3; ZNF10; SFMBT1; SLC2A4RG; CREB3L2; SF1; RLF; IRF1; LEF1; REPIN1; MED1; ZNF165; ELF5; ZNF551; PITX1; CEBPA; HIC2; HMGB2; TCF21; ATF3; HOXB6; WT1; LITAF; MSX1; ZNF91; PEG3; FOXF1