Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17094 Geldanamycin GSE70138 MCF10A Human 3h 0.37uM EID0009
Types Number Response transcription factors
Up-regulation 32 DDIT3; ZNF165; PPARG; ZNF473; NR0B1; PBXIP1; ATF3; TAF9B; POU2AF1; CREBL2; E2F2; RAD21; FOXF1; CREM; ZNF652; KLF5; PIR; DBP; SSX1; NKX2-2; TRIP6; RBPMS; TFEC; FOXF2; TBX3; CALR; PAX6; KLF11; ZNF331; PBX1; ZBTB38; BHLHE41
Down-regulation 24 MYC; NFKBIA; HMGA2; HES1; EGR1; ZFP36L2; ADRB2; SMAD3; PRKDC; FOSL1; ZBTB7A; ZNF593; ELK3; TSC22D3; LMCD1; ZEB1; EGR3; TLE1; BACH2; THAP11; ZHX2; NR2F2; NFIL3; ERBB2