Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17083 Withaferin-a GSE70138 MCF10A Human 3h 0.12uM EID0009
Types Number Response transcription factors
Up-regulation 33 SSBP2; XBP1; SIX1; FOXD1; EGR1; RBBP5; NCOA1; TRIM16; MAFB; KDM2A; RBBP4; NKX3-1; BCL11B; HMGN3; FLNA; MED1; PAX5; CTNNB1; ERBB2; ERG; SOX9; HOXC10; CTR9; HOXC6; SMARCA2; AFF1; IRX5; ELK3; BRD2; HMGA1; FOSB; EGR3; LEF1
Down-regulation 44 PUF60; NR2F6; KLF6; PLAGL1; TCEA2; MECOM; ZNF165; SNAI2; HOXD3; KAT2B; ELF5; TEAD4; ZNF268; ZNF623; KLF5; FEZF2; TP63; TCF21; STAT4; WT1; BARX1; TLE4; ATF3; ID4; PAWR; NR5A2; BHLHE41; ARNT2; ZSCAN18; ZFP36L2; PBX1; IRF9; PBX3; JUN; HOXD1; ID3; TFAP2C; NFE2; VPS72; ARID5B; GATA6; MEIS2; SOX17; TBX2