Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17079 Withaferin-a GSE70138 MCF10A Human 3h 10uM EID0009
Types Number Response transcription factors
Up-regulation 52 EGR1; POU4F1; ATF4; XBP1; FOS; TERF2; DDIT3; MYB; ATF3; SUB1; PTRF; SOX4; MSX1; TBP; KLF4; MLXIP; INSR; RORA; BTG1; BRD4; JUNB; RBM39; ATF7IP; RLF; KLF5; JUN; NR4A1; FOSB; RYBP; HOXB7; ID2; KLF2; SMAD7; IRF7; TRIM16; KAT6B; ZNF281; ERG; MYCN; RFX5; FOXE1; NKX2-1; TAL1; PITX2; POU2AF1; EGR3; JUP; ZFP36L2; ZNF423; ESR1; LEF1; BASP1
Down-regulation 28 MYC; LITAF; NELFB; NFKBIA; AHR; STAT3; TRPS1; ENO1; HES1; NFIB; WWTR1; ZMYND11; PBX3; ADRB2; NAB1; MEIS1; TSC22D1; BAZ1A; NR2F1; ZNF665; ZIC1; EYA1; MYBL1; HEY1; WT1; VPS72; SATB1; E2F2