Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17078 Mitoxantrone GSE70138 MCF10A Human 3h 0.04uM EID0009
Types Number Response transcription factors
Up-regulation 67 TRIM22; ZNF430; ZNF274; ZNF12; NFE2L3; MED17; ZNF611; ZNF551; CERS6; ZKSCAN1; MDM2; ZNF652; KAT2B; BTG1; ZNF224; ZBTB20; MYRF; ZNF140; ZNF160; TOX3; CERS4; THAP10; ZNF665; TLE4; JAK2; BACH1; MYBL1; WT1; MNDA; CITED2; HLX; HBP1; ID4; BNC2; ZNF85; ZNF273; TCF21; PAWR; TRIB3; IRF8; CTBP2; HDAC9; AEBP1; HIC2; CREB3L2; TBX3; GATA6; ZNF43; PBX3; JUP; ZNF91; KLF11; TCEA2; SNAI2; BCL11A; NR5A2; ZHX2; ARID5B; ZNF117; IRF9; TCF4; MYCL; ARNT2; BHLHE41; ZFPM2; VPS72; MEIS2
Down-regulation 27 YBX1; PITX1; NKX3-1; TAF10; GTF3A; STAT5B; HNRNPD; SMAD2; TP53; NCOR2; CBFB; MSX1; BCL11B; HLTF; IRX5; SMAD7; HEY1; SMARCA1; EYA2; HOXC10; CTR9; YWHAB; KLF2; HOXC6; ELF1; FOXG1; SUV39H1