Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17076 Mitoxantrone GSE70138 MCF10A Human 3h 0.37uM EID0009
Types Number Response transcription factors
Up-regulation 22 NFKBIA; HOXA10; TRIM22; ESR1; EGR1; NR1H2; ATF3; OSR2; STAT6; JUN; IFI16; JUNB; MAGED1; TRIP6; EMX2; MSX1; ZBED2; FOSB; NKX2-1; WT1; ELK3; FOS
Down-regulation 38 MYC; ZBTB16; HMGA2; HMBOX1; ZBTB18; SPEN; WWTR1; HMGB2; HIPK2; MECP2; ARID1A; TOX3; CHD9; NKX3-1; TRIB3; KLF9; NFAT5; SOX9; CREB1; HIRA; TWIST1; FOXG1; NFIB; CTBP2; TSC22D2; INSR; ZHX2; FOXF1; ZNF91; CBFB; EYA1; KDM5D; MYRF; SOX11; PBX3; NFIL3; HOXC6; SATB1