Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17075 Mitoxantrone GSE70138 MCF10A Human 3h 1.11uM EID0009
Types Number Response transcription factors
Up-regulation 30 NFKBIA; EGR1; RELB; ATF3; ZNF274; NHLH2; CALCOCO1; SSX1; AEBP1; JUNB; IRF1; BCL3; OSR2; JUN; ZIC1; NR4A1; IFI16; FOXN3; ST18; FOSB; CRYM; PAX6; HOXD1; MEOX2; FOS; ZFPM2; MYRF; PBX3; EGR2; MEIS2
Down-regulation 22 MYC; CCNA2; FHL2; HOXA10; SMAD3; HMGA2; TOB1; PURA; FOXD1; ZMIZ1; CENPF; ID1; PTTG1; HIRA; ID4; SATB2; ADRB2; JARID2; ZFP36L2; TOX3; NFIL3; E2F2