Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17074 Mitoxantrone GSE70138 MCF10A Human 3h 3.33uM EID0009
Types Number Response transcription factors
Up-regulation 31 EGR1; EGR2; HSBP1; OLIG2; TRIM24; LMCD1; AEBP1; MYB; NRBF2; ATF3; JUN; WWC1; BHLHE41; EN1; ASCL1; FOSB; RUNX1; HTATIP2; ZFPM2; BCL6; CBFA2T3; MAF; FOS; GATA6; ID2; HEY1; TOX; ST18; IRF8; HOXD1; SOX11
Down-regulation 49 MYC; HMGA2; HOXA10; CCNA2; HOXA5; ADRB2; FHL2; ETS1; BHLHE40; NR3C1; FOXO3; FOXD1; SMAD3; CEBPB; CRK; CHD1; ARID1A; KLF7; HOXA1; NRIP1; ZMYND8; VEZF1; FOSL1; TSC22D2; SMAD1; MECOM; ZNF281; MSX1; AFF1; TGIF1; ZBTB38; KLF9; TLE1; SMAD7; HOXB2; YWHAB; ING3; BTG1; TSC22D1; ZFP36L1; CREB1; PIR; ISL1; NFIL3; ELK3; SUV39H1; ERBB2; NR2F2; SATB1