Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17073 Mitoxantrone GSE70138 MCF10A Human 3h 10uM EID0009
Types Number Response transcription factors
Up-regulation 18 BHLHE40; HSBP1; ZNF226; SSX1; MYB; ADRB2; RBPMS; ZSCAN18; HMGB3; ID4; TCF7L1; DACH1; TCF4; AEBP1; TCF21; JUP; PBX3; PEG3
Down-regulation 73 MYC; NFKBIA; HOXA5; MED17; JUNB; FHL2; HOXA10; ARID4B; CCNA2; HMGA2; PLAGL2; IKBKAP; SNIP1; SMAD3; BCL10; ADNP; ZNF443; HES1; CHD1; FOSL1; ZBTB16; FOXJ3; RNF138; ZZZ3; CEBPD; CEBPB; ZNF189; RLF; NRIP1; HOXB7; VEZF1; RNF111; CCNE1; ZBTB1; TRIM32; SMAD7; TAF1D; CCDC59; AHR; EGR3; FOXD1; MTF2; MYBL1; KLF10; KAT6A; NFIL3; NRBF2; E2F8; ZBTB11; SAP30; SOX10; EGR1; RUNX3; ING3; ZNF107; NR4A1; TSC22D2; CITED2; ZFP36L1; NR4A2; BTG1; ETV5; ID2; ZNF124; SFPQ; EGR2; FOS; ELK3; JUN; CREB1; NR2F2; SUV39H1; BASP1