Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17053 Linsitinib GSE70138 MCF10A Human 3h 0.12uM EID0009
Types Number Response transcription factors
Up-regulation 19 TBL1XR1; FOXJ3; HTATIP2; ZNF165; KLF9; SOX10; TFAP2C; AHR; NCOA3; ELF5; CREB3L2; TFEC; ZIC1; RUNX3; IRF8; IFI16; NR2F1; MAFB; HEY1
Down-regulation 13 IKBKAP; NKX3-1; SIX1; PITX1; PDLIM1; ETS1; EYA2; HOXC10; ISL1; LOXL2; KDM5D; NR2F2; HOXC6