Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17050 Linsitinib GSE70138 MCF10A Human 3h 3.33uM EID0009
Types Number Response transcription factors
Up-regulation 34 TSC22D3; LITAF; MITF; ZNF274; MAF; TP63; EGR2; TCF25; FOXN3; GRHL2; THAP10; ZNF350; ZNF12; CREBL2; FOXA1; ZNF268; NCOA3; BHLHE41; MYBL1; JUP; CRYM; KLF4; SMARCA2; BNC2; TLE4; NFE2L3; RBPJ; CITED2; ZFPM2; MYCL; NANOG; PBX3; SOX11; FOS
Down-regulation 19 FOXD1; ARID4B; BCL3; SPEN; GTF3A; RBM14; HMGN3; CREB1; KLF10; BHLHE40; DLX2; MSX1; FOXC1; ETS2; FOXG1; SOX9; DLX5; FOSL1; HOXC6