Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17047 Ruxolitinib GSE70138 MCF10A Human 3h 0.12uM EID0009
Types Number Response transcription factors
Up-regulation 26 SMAD3; FOXJ3; ADRB2; FOXC1; MEF2A; BHLHE40; HMGB3; RFX5; ABL1; BCL11B; SMAD7; SATB1; ELK3; KLF9; ETS2; PURA; HLTF; MAFB; MAF; JARID2; HOXC10; ASCL1; HMGA1; ELF1; ID1; HOXC6
Down-regulation 36 ZNF652; E2F8; ZKSCAN1; FOXN3; INSM1; PAX6; HIRA; BHLHE41; FOS; TFEC; NFE2L3; TCEA2; ZHX2; MNDA; ZFP36L2; NEUROD1; IFI16; MEIS1; FOXF2; WT1; MXI1; EMX2; PEG3; GATA6; MYRF; ST18; NR5A2; MYBL1; ZNF532; ARNT2; ARID5B; ZFPM2; HOXD1; SOX17; VPS72; MEIS2