Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17045 Ruxolitinib GSE70138 MCF10A Human 3h 1.11uM EID0009
Types Number Response transcription factors
Up-regulation 50 MNAT1; DAXX; GTF2IRD1; IKZF1; ZIC1; MAFB; NR2F1; ETS2; ZNF217; DACH1; MYB; TBL1XR1; ARID5B; SIX1; PROX1; MECOM; TBX2; PRRX1; KLF9; PLAGL1; SNAI2; ZEB2; KLF4; HDAC1; TWIST1; SOX9; NCOR2; TOB1; DNAJC2; TRPS1; BACH1; RBBP4; TRIM29; FOXF1; HLX; NPAS2; FOXC1; HMGB3; LOXL2; LEF1; ZBTB18; ZNF467; EGR3; ID4; ELK3; SATB2; KLF2; MEOX2; FOXG1; BASP1
Down-regulation 39 KLF6; ZFP30; ZNF536; ZNF133; CARHSP1; PEG3; ZNF551; RAD21; NKX2-2; NR0B1; RBPMS; HTATIP2; SOX10; EDF1; CREB5; NHLH2; APEX1; DLX5; PURA; TXNIP; ZNF83; CITED1; BBX; HIRA; INSM1; ELF5; CREB3L2; TBL1X; MYBL1; ZNF532; KLF11; FOS; MYRF; ST18; GLI2; NANOG; ESR1; MEIS2; SATB1