Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17043 Ruxolitinib GSE70138 MCF10A Human 3h 10uM EID0009
Types Number Response transcription factors
Up-regulation 35 HDAC6; KDM5D; EGR1; LITAF; NFKB1; BHLHE40; SRF; MXI1; KLF9; CBX6; XBP1; IRX5; EMX2; ZNF589; HMGA2; ELF4; ELF3; INSM1; HMGA1; NR1D2; MECOM; HMGN3; RUNX3; NAB1; FOSB; TOX; AHR; BCLAF1; TWIST1; FLNA; MYRF; ELK3; ERBB2; ZBTB38; ID1
Down-regulation 43 EED; TBP; ZMYM2; PSPC1; SMARCD3; BRCA1; PMS1; ZNF302; MYB; ZNF544; MLXIP; SAP30; ADRB2; FOXL2; ZNF160; ERG; ELF5; TRIM22; HMGB2; HLX; FOXO1; PITX2; BACH2; TXNIP; KLF2; PAX5; ZNF93; KLF4; TLE4; WT1; FOS; INSR; JUN; TCF4; TCF21; TLE1; IFI16; NFE2; HOXB2; MEOX2; GATA6; PEG3; E2F2