Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17042 Alpelisib GSE70138 MCF10A Human 3h 0.04uM EID0009
Types Number Response transcription factors
Up-regulation 30 KDM5D; SMAD3; SMAD6; VGLL1; TEAD4; KAT6B; FOXN3; MYT1L; MXI1; MEIS2; EHF; ZIC1; HDAC9; ERG; GATA2; ZNF423; WT1; TFEC; NR2F1; MECOM; PAX6; ZFPM2; TOX; NR5A2; BHLHE41; TWIST1; ZEB1; ID4; MEIS1; PEG3
Down-regulation 23 HMG20B; TCF7; NCOA6; PRKDC; BCL3; SPEN; TBL1X; CENPB; MLXIP; MED14; TRIM29; TLE4; TOB1; TSC22D2; SCAND1; BACH2; JUN; TOX3; ELF1; MAFB; HOXB2; BASP1; E2F2