Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17039 Alpelisib GSE70138 MCF10A Human 3h 1.11uM EID0009
Types Number Response transcription factors
Up-regulation 43 KDM5D; NCOA1; BAZ2B; FOXN3; ZNF22; TFEC; SMAD6; TSC22D3; RXRA; ETS2; MNDA; KLF9; HBP1; ID4; HEY1; ZIC1; MYB; TCF7L2; NCOA3; EN1; BCL11A; PAX6; BTG1; FOXF2; DACH1; SOX9; ZHX2; SNAI2; IRF6; PAWR; FLI1; GATA6; ZBTB20; SOX2; SOX11; MEIS2; ZNF117; IRF9; FOS; ARNT2; ERBB4; VPS72; PBX3
Down-regulation 14 NR2F6; HMG20B; CREB3L1; SCAND1; IRF4; MLXIP; PITX1; EYA2; ESR1; HOXB2; PIR; YWHAB; ELK3; NR2F2