Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17037 Alpelisib GSE70138 MCF10A Human 3h 10uM EID0009
Types Number Response transcription factors
Up-regulation 38 TSC22D3; NR3C1; HOXA5; BTAF1; ZNF165; FOXN3; HBP1; ZBTB16; PNRC1; TGIF1; TBL1XR1; ID4; ZNF133; TRIM29; CCNC; CREBL2; NCOA2; BTG1; KLF5; KLF9; MXI1; TCF4; MNDA; TLE4; MAF; TXNIP; ZHX2; HIRA; JUP; ID3; PBX3; ST18; MAFB; TCF21; MYCL; GATA6; SOX11; BASP1
Down-regulation 24 RREB1; PRRX1; KLF10; HOXA11; NFIC; SPEN; EYA2; BHLHE40; IRX5; FOSL1; PITX1; ETV5; BRD2; MSX1; NR2F2; EGR3; FLNA; YWHAB; LEF1; ASCL1; ESR1; FOS; SATB1; E2F2