Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17032 Nvp-bez235 GSE70138 MCF10A Human 3h 3.33uM EID0009
Types Number Response transcription factors
Up-regulation 70 TSC22D3; KLF6; KDM5D; MLLT10; FOXN3; LITAF; CHD9; HDAC5; IRF1; HBP1; BTG1; ATF3; CALCOCO1; TTF2; HIPK1; DDIT3; TP63; SRCAP; PNRC1; ZNF654; TLE4; SUPT3H; ZNF611; HEY2; ING4; SUPT4H1; PRDM2; SNAI2; EP300; ZNF91; FOXF1; TCF21; TBX2; INSR; TLE2; CBX7; KLF5; REL; PHIP; JUP; ZNF83; ELF5; PBX3; FOSB; ZNF500; CITED2; KAT2B; FOXF2; IRF6; ZSCAN18; PAX6; PLAGL1; LOXL2; TFAP2C; IFI16; MYBL1; ID3; WNT4; MEIS1; TRIB3; MEIS2; ZNF331; NR4A2; ZNF117; KLF2; MYCL; NANOG; FOS; SOX11; VPS72
Down-regulation 37 ZNF146; XBP1; THAP1; ZBTB18; SPEN; CCNE1; RBM14; PA2G4; TRIM32; ESR1; SFPQ; NKX3-1; BHLHE40; HNRNPD; TFAM; NUP62; ING3; BAZ1A; CTR9; EMX2; CEBPZ; SMAD7; EGR3; MED1; MAGED1; THAP11; HOXC6; TSC22D1; RUNX3; PIR; IRX5; TLE1; FOSL1; ZBTB38; ELK3; MAFB; SUV39H1