Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17031 Nvp-bez235 GSE70138 MCF10A Human 3h 10uM EID0009
Types Number Response transcription factors
Up-regulation 25 TSC22D3; KLF6; NR3C1; MBD2; PTTG1; TRIM22; LITAF; KDM5D; RBBP4; TBL1XR1; KLF2; AES; JUND; KAT6B; FOSB; SATB1; MAFB; HOXC6; ATF3; ERBB2; FLNA; MYBL1; ELF1; ID4; BASP1
Down-regulation 55 NKX3-1; PLAGL2; MKL2; MED17; ILF2; ZNF195; PPRC1; RNF138; CCNE1; TAF1A; HMBOX1; FOXF1; SMARCA1; CREB1; HIC2; ZNF331; BRD4; HLX; RNF6; SSX1; FOXA2; IRF4; ZNF124; EMX2; RYBP; FOXF2; AR; JUN; ZNF711; ZNF141; PKNOX2; PHIP; MAGED1; SALL1; EGR3; MEIS1; NEUROD1; WT1; AHR; ZNF423; TOX; NR5A2; ERBB4; HOXD1; TCF21; HEY1; DACH1; MEIS2; PBX3; ID3; VPS72; MYRF; PPARG; LEF1; TBX2