Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID17005 Pik-93 GSE70138 MCF10A Human 3h 0.12uM EID0009
Types Number Response transcription factors
Up-regulation 30 DEAF1; SOX4; EYA2; FLNA; CHD7; MAZ; BAZ1A; CTNNB1; EGR1; MAX; TGIF1; CENPF; KLF10; AFF1; HOXC6; HOXB7; NR2F2; BRD2; CTR9; ELF1; LEF1; RBBP4; IRX5; HMGB3; SMARCA2; HMGA1; HOXC10; HLTF; SATB1; ASCL1
Down-regulation 78 SMAD6; ANKRD1; MECOM; CREM; TCEA2; KAT2B; ZNF165; PRRX1; SOX2; MYCN; ZNF112; ZNF180; PLAGL1; HOXD1; PAWR; ZNF268; ZNF257; ZNF573; ZNF232; EMX2; ISL1; ARNT2; NANOG; TWIST1; SNAI2; E2F8; NFE2L3; ZFP69B; HOXD3; FEZF2; ZNF141; SOX18; ZHX2; CEBPB; NR1H4; NFATC4; SHOX2; LIN28A; ZNF85; EHF; DLX5; FOS; ZSCAN18; TAL1; SOX3; TFEC; ZNF124; HDAC9; SALL2; INSM1; BNC2; ZIC3; PBX1; WT1; GLI2; SOX17; CREB1; CITED2; MYBL1; ZNF423; HIC2; TCF21; SOX11; ZEB1; IRF9; NFE2; JUP; ARID5B; PEG3; NFATC3; MEIS2; ZNF117; ZBTB20; VPS72; MYCL; CUX2; MYRF; ZFPM2