Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16993 Pf-477736 GSE70138 MCF10A Human 3h 0.37uM EID0009
Types Number Response transcription factors
Up-regulation 30 SSBP2; ZMYM2; TSC22D3; XBP1; DNAJC1; EGR1; IRX5; ATF4; HSBP1; FOXD1; PSPC1; MEF2A; TCF25; BAZ1A; PTTG1; BHLHE40; CEBPG; MYB; ELF1; BMI1; CTNNB1; IRF7; HMGB1; EYA2; SMARCA2; PIR; LEF1; JARID2; HOXC6; FOSB
Down-regulation 111 ARNT2; HIPK2; ZNF215; TP63; ZFHX4; TERF2; SSX1; ARL2BP; FOXN3; TLX3; ZNF334; SHOX2; HOXB13; TBR1; ISL1; ZFPM2; SMARCA1; AR; MECP2; YEATS4; BNC2; TBX21; POU4F3; SOX14; INSM1; LHX3; CDIP1; RORC; TCEA2; GATA1; BACH1; NEUROG2; L3MBTL1; RBFOX2; FEZF2; VGLL1; GFI1B; VENTX; SOX21; ANKRD1; ZNF512B; ZNF573; NFIB; NKX2-2; NFE2L3; WT1; CARF; NR5A2; RXRG; BRD4; HBP1; PRDM14; FOXG1; SALL2; CHD2; MYRF; ZNF345; FOXF2; IRF6; NFATC4; MEIS2; SNAI2; ZNF532; ZBTB20; ZNF180; NR2F1; ZNF589; NR1H4; TCF7L1; EN1; MECOM; TULP3; MNDA; JAK2; TCF7L2; BHLHE41; TBX3; TCF21; ZNF75D; HOXB2; PKNOX2; ZNF141; MEOX2; MEIS1; ARID5B; SIX3; TWIST1; EHF; HDAC9; EMX2; ZNF423; HOXD1; NANOG; TRIM29; NEUROD1; SOX2; ZNF43; KLF11; ZEB1; CUX2; GLI2; FOXF1; NFATC3; IRF8; SOX11; ID3; SOX17; PEG3; IRF9; PBX3; SATB1