Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16983 Roscovitine GSE70138 MCF10A Human 3h 0.04uM EID0009
Types Number Response transcription factors
Up-regulation 20 XBP1; TRIM16; SIAH2; IKBKAP; TSC22D1; PITX1; POLR2A; PURA; MAGED1; FLNA; PCGF2; TRIP6; ELK3; FOSB; THAP11; SATB2; AFF1; HOXC6; HMG20B; KDM5D
Down-regulation 50 CDK2; NKX2-2; RARA; ARNT2; SOX10; PRDM12; HOXD1; RYBP; NFATC4; ZNF331; KLF10; DLX5; TOX; PBX3; ANKRD1; WT1; NR1H4; ZEB1; ZFPM2; FEZF2; DLX2; SCAND1; SOX2; NFE2; ZNF232; KAT2B; NR5A2; TAL1; NKX2-1; SOX3; ERBB4; INSR; BNC2; ZNF512B; IRF9; MYBL1; SOX17; TRPS1; VPS72; HOXB2; CUX2; MYRF; TCF21; ZNF423; SOX11; GATA6; NFATC3; MEIS2; ARID5B; ID1