Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16979 Roscovitine GSE70138 MCF10A Human 3h 3.33uM EID0009
Types Number Response transcription factors
Up-regulation 70 SP140L; LITAF; POU4F1; ZNF195; ZNF557; MKL2; SRY; RNF138; MYB; ZKSCAN1; RYBP; HIRA; SSX1; ZNF12; DMRT1; E2F8; ZNF623; CUX1; ZNF257; TEAD4; HIC2; AEBP1; BCL11A; NFE2L3; ZNF682; SOX18; MYRF; TULP3; ZNF331; NR1H2; NR1H4; ZNF85; NR5A2; SOHLH2; SHOX2; ZFP36L2; CRYM; NCOA3; TXNIP; TRIB3; MYCN; TCF21; MECOM; MYBL1; TAL1; SOX13; CBFA2T3; TFAP2C; TCF7L2; SOX3; ZNF124; WNT4; WT1; SIX3; NFATC4; SOX17; ZNF43; CREB3L2; FOXF1; MEIS2; IRF9; HOXD1; SOX2; ZEB1; ARNT2; CUX2; GATA6; ERBB4; VPS72; SOX11
Down-regulation 18 ZBTB18; PITX1; TRIM16; ZEB2; TOB1; SMARCA2; SOX9; FOSB; TRIP6; THAP11; FLNA; AHR; EGR3; ELF1; MAFB; HOXC6; BASP1; SUV39H1