Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16978 Roscovitine GSE70138 MCF10A Human 3h 10uM EID0009
Types Number Response transcription factors
Up-regulation 17 CEBPD; EGR1; RBBP8; NR4A1; OSR2; NFE2L3; TSC22D1; ESR1; TAL1; SOX9; FOXG1; IRF8; EGR3; MEOX2; WT1; ASCL1; FOS
Down-regulation 25 ADRB2; USP22; NR2F6; ADNP; CREB1; KLF6; KLF7; DNMT3B; SMARCA1; SERTAD2; TLE1; RORA; BLM; BTG1; CITED2; ZBTB38; SMAD7; JUN; TRIP6; JARID2; YWHAB; ID3; KLF2; ZHX2; ERBB2