Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16975 Torin-2 GSE70138 MCF10A Human 3h 0.37uM EID0009
Types Number Response transcription factors
Up-regulation 84 TSC22D3; SOX4; ZMYND8; BTG1; LITAF; KLF6; HBP1; SP100; MEOX1; PNRC1; ZNF160; ZKSCAN1; WWP1; EZH1; RAD21; ING4; DDIT3; ADRB2; ZBTB16; TOX3; TCF7L2; BPTF; ZNF248; MXI1; ZNF573; FOXN3; HEY2; TXNIP; L3MBTL1; MAF; FOXO1; TRPS1; KLF4; CARF; ZNF611; ZIC1; MECOM; ZBTB44; BCL11A; ZNF224; FOXF1; REL; GLI2; ZNF623; PAWR; ZNF500; FOXF2; ZNF217; TCF7L1; ZNF665; ZNF93; ZNF43; NCOA3; HMGB2; TOB1; MYB; AEBP1; SOX2; TCF21; SALL2; GATA6; ZNF85; SOX11; CREB3L2; HMGB3; SNAI2; PBX3; MAFB; NFATC4; ZNF91; BRD2; PBX1; TCF4; ZNF423; CTBP2; IRF9; DACH1; YWHAB; NANOG; HOXD1; CUX2; VPS72; FOS; PEG3
Down-regulation 32 GMNN; ZNF146; PITX1; EED; NUP62; XBP1; BCL3; RUVBL2; CCNE1; NKX3-1; EGR1; RBM14; PPRC1; TRIP6; ZBTB18; TRIM28; BHLHE40; CEBPZ; CBFB; JUNB; BAZ1A; FOSL1; RUNX3; HLTF; JARID2; IRX5; FLNA; MAGED1; THAP11; ERBB2; ELK3; SATB1