Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16974 Torin-2 GSE70138 MCF10A Human 3h 1.11uM EID0009
Types Number Response transcription factors
Up-regulation 33 TSC22D3; NR3C1; KDM5A; ZBTB16; ATF4; ZMIZ2; EZH1; PSPC1; KLF6; TXNIP; TAF1D; BRD8; LITAF; ELF5; RAD21; CITED2; HBP1; ARID4B; ABL1; HMGB2; KLF5; PNRC1; KLF4; STAT6; BRD2; PAWR; ELF1; BCL11A; JUP; FOSB; MAFB; KDM5D; BASP1
Down-regulation 40 ZNF146; HES1; TCEA2; HMGA2; CCNE1; HOXB2; NKX3-1; JUNB; PRRX1; TRIM32; MEIS1; HOXB6; SMAD1; ZIC1; MYT1L; IRF4; WWC1; RUNX1; HLX; JUN; MAGED1; FOSL1; SCAND1; NKX2-2; MYCN; TOX; TRIP6; WT1; LEF1; FLNA; ID3; ZFPM2; ZEB1; ZNF423; ELK3; EGR2; MEIS2; GATA2; SATB1; E2F2