Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16973 Torin-2 GSE70138 MCF10A Human 3h 3.33uM EID0009
Types Number Response transcription factors
Up-regulation 53 TSC22D3; ZMYM2; PSPC1; NR3C1; SOX4; NR1D2; KLF6; EZH1; DDIT3; RAD21; TXNIP; HBP1; ZIC1; FOXO3; HMGB2; HOXB6; ZNF536; ID2; CALCOCO1; ATF4; BRD8; HDAC5; PPARGC1A; E2F2; HOXB7; ZNF217; BTG1; SAP30; INSM1; PRKDC; PNRC1; SMARCA1; HOXB5; AEBP1; EHF; ZNF93; MAF; DLX2; ID3; TOB1; RBPMS; ASCL1; CRYM; HDAC9; CITED2; DLX5; ATF3; HMGA1; KDM5D; TBX3; PAX6; ZBTB20; ST18
Down-regulation 32 FHL2; HOXA10; HES1; ADRB2; MYC; TAF9; PPRC1; TFAM; RNF138; PITX1; NUP62; HMGA2; FOSL1; CEBPZ; BHLHE40; ZFP36L1; SUB1; SCAND1; EGR1; WWC1; THAP11; WT1; ZNF512B; NR2F1; HIC2; MNDA; FOS; LEF1; PBX1; SOX9; EMX2; SOX11